Mouse IL6 / Interleukin 6

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

Unconjugated

Purified

Unmodified

Neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNF-alpha nor does it bind to either human or rat IL-6. Inhibits IL-6 induced proliferation of the B9 assay.

• Functional Assay
• Neutralization

Can be used for in vitro and in vivo inhibition of activity of IL-6. Furthermore the antibody is useful for Immunochemical investigations of mouse IL-6 in structural studies and for quantitative/qualitative immunochemical detection methods. May be used as a coating antibody in immunoassay procedures. For neutralization of biological activity dilutions have to be made according to the amount of IL-6 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

PBS, 0.02% Sodium Azide, 0.1% BSA

Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P05231 NCBI: NM_000600 NP_000591.1