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IL17RA

interleukin 17 receptor A

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: interleukin 17 receptor A
Family/Subfamily: Interleukin
Synonyms: IL17RA, CANDF5, CD217 antigen, CDw217, CD217, HIL-17R, IL-17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor, IL-17 receptor A, Interleukin 17 receptor, Interleukin 17 receptor A
Target Sequences: NM_014339 NP_055154.3 Q96F46

Publications (3)

1
COX-2 modulates mammary tumor progression in response to collagen density. Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. Breast cancer research : BCR. 2016 18:35. (WB; Human) [Full Text Article] [PubMed:27000374] [PMC:PMC4802888]
2
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation. Tao Peng, R Savanh Chanthaphavong, Sijie Sun, James A Trigilio, Khamsone Phasouk, Lei Jin, Erik D Layton, Alvason Z Li, Colin E Correnti, Willem De van der Schueren, Julio Vazquez, Diana R O'Day, Ian A Glass, David M Knipe, Anna Wald, Lawrence Corey, Jia Zhu. The Journal of experimental medicine. 2017 August;214:2315-2329. [Full Text Article] [PubMed:28663436] [PMC:PMC5551564]
3
Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. Travis K Hughes, Marc H Wadsworth nd, Todd M Gierahn, Tran Do, David Weiss, Priscila R Andrade, Feiyang Ma, Bruno J de Andrade Silva, Shuai Shao, Lam C Tsoi, Jose Ordovas-Montanes, Johann E Gudjonsson, Robert L Modlin, J Christopher Love, Alex K Shalek. Immunity. 2020 October;53:878-894.e7. [Full Text Article] [PubMed:33053333] [PMC:PMC7562821] Related Antibodies: LS-C359381.

☰ Filters
Antibodies (82)
Proteins (16)
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IL17RA (104)
Human (58)
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monoclonal mc (17)
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IL17RA Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
IL17RA Antibody - Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 ug/ml.
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IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
IL17RA Antibody - Immunohistochemistry-Paraffin: IL17RA Antibody (49M4D2) - Formalin-fixed, paraffin-embedded human spleen stained with IL-17RA antibody (1 ug/ml), peroxidase-conjugate and DAB chromogen. TMA was used for this test.
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IL17RA Mouse anti-Human Monoclonal (aa186-267) (49M4D2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
IL17RA Antibody - Immunohistochemistry-Paraffin: IL17RA Antibody (49M4D2) [Azide Free] - Formalin-fixed, paraffin-embedded human spleen stained with IL-17RA antibody (1 ug/ml), peroxidase-conjugate and DAB chromogen. TMA was used for this test. This image was taken for the unmodified form of this product. Other forms have not been tested.
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IL17RA Mouse anti-Human Monoclonal (aa186-267) (Azide-free) (49M4D2) Antibody
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
IL17RA Antibody - Staining of Rat Kidney lysate (35 ug protein in RIPA buffer) with IL17RA antibody (1 ug/ml). Primary incubation was 1 hour. Detected by chemiluminescence.
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IL17RA Goat anti-Mouse Polyclonal (aa353-364) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$503
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IL17RA Rat anti-Mouse Monoclonal (aa32-322) (APC) (12K116) Antibody
Mouse
Flo
APC Conjugated
100 Tests/$884
Select
IL17RA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
IL17RA ELISA Kit
Select
Sandwich
96-Well Microplate
Human
12.35 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
IL17RA Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
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IL17RA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
60 µl/$460
Select
IL17RA Goat anti-Mouse Polyclonal (Extracellular Domain) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$929
Select
IL17RA Mouse anti-Human Monoclonal (aa33-320) Antibody
Human
ELISA, WB
Unconjugated
500 µg/$1,089
Select
IL17RA Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
IL17RA Rabbit anti-Human Monoclonal (FITC) (004) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$421
IL17RA Antibody - Western blot analysis using CD217 mAb against HEK293 (1) and CD217 (AA: extra 33-320)-hIgGFc transfected HEK293 (2) cell lysate.
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IL17RA Mouse anti-Human Monoclonal (6H1B1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
IL17RA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$795
IL17RA Antibody - Western blot analysis of extracts from LOVO cells, using IL17RAantibody.
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IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
IL17RA Antibody - Staining LOVO cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
IL17RA Rabbit anti-Mouse Polyclonal (aa721-747) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
Select
IL17RA Rabbit anti-Mouse Polyclonal (aa721-747) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
IL17RA Antibody - Fig-1: Western blot analysis of IL-17 RA. Anti- IL-17 RA antibody was used at 4 µg/ml on h Intestine lysate.
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IL17RA Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
25 µg/$288; 100 µg/$414
Select
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
IL17RA Rabbit anti-Human Polyclonal (110-190 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL17RA Antibody - Western blot analysis of IL17RA using anti-IL17RA antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: human Hela whole cell lysate,Lane 2: human HepG2 whole cell lysate,Lane 3: human MCF-7 whole cell lysate. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-IL17RA antigen affinity purified polyclonal antibody at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for IL17RA at approximately 160KD. The expected band size for IL17RA is at 96KD.
Select
IL17RA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL17RA Antibody - Recombinant proteins were subjected to SDS PAGE followed by western blot with IL17RA antibody at dilution of 1:1500
Select
IL17RA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
IL17RA Rat anti-Mouse Monoclonal (aa32-322) (11n105) Antibody
Mouse
Flo
Unconjugated
100 µg/$962
Viewing 1-25 of 104 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).