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DRD1 / Dopamine Receptor D1
dopamine receptor D1
DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension.
| Gene Name: | dopamine receptor D1 |
| Family/Subfamily: | GPCR , Dopamine |
| Synonyms: | DRD1, D(1A) dopamine receptor, DRD1A, DADR, D1a receptor |
| Target Sequences: | NM_000794 NP_000785.1 P21728 |
Publications (2)
1
Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors. Laurent Ladepeche, Julien P Dupuis, Delphine Bouchet, Evelyne Doudnikoff, Luting Yang, Yohan Campagne, Erwan Bézard, Eric Hosy, Laurent Groc. Proceedings of the National Academy of Sciences of the United States of America. 2013 October;110:18005-10. [Full Text Article]
[PubMed:24127604]
[PMC:PMC3816474]
Related Antibodies: LS-C86998.
2
Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma. Yan Yan, Jiahao Pan, Yonghua Chen, Wei Xing, Qiang Li, Dongyin Wang, Xiaoshuang Zhou, Jingdun Xie, Changhong Miao, Yunfei Yuan, Weian Zeng, Dongtai Chen. Cancer communications (London, England). 2020 December;40:694-710. [Full Text Article]
[PubMed:33017522]
[PMC:PMC7743025]
Related Antibodies: LS-A44.
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Neuroscience
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Dog, Bovine, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
Neuroscience
Fast Shipping
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (aa187-232) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DRD1 / Dopamine Receptor D1 Mouse anti-Rat Monoclonal (C-Terminus) (SG2-D1a) Antibody
Mouse, Rat
IHC, WB
Unconjugated
100 µg/$854
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$386
E. coli
His, N-Terminal
15.5 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$856
DRD1 / Dopamine Receptor D1 Rabbit anti-Rat Polyclonal Antibody
Rat
Unconjugated
100 µg/$754
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (aa338-446) Antibody
Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DRD1 / Dopamine Receptor D1 Rabbit anti-Rat Polyclonal (4th Extracellular Domain) Antibody
Rat
ELISA, WB
Unconjugated
100 µg/$832
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DRD1 / Dopamine Receptor D1 Mouse anti-Rat Monoclonal (C-Terminus) (SG2-D1a) Antibody
Mouse, Rat
ICC, IF, WB
Unconjugated
0.1 ml/$386
DRD1 / Dopamine Receptor D1 Rabbit anti-Rat Polyclonal (aa9-21) Antibody
Rat
ELISA, IHC, WB
Unconjugated
100 µl/$775
DRD1 / Dopamine Receptor D1 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$513; 100 µg/$832
DRD1 / Dopamine Receptor D1 Rabbit anti-Rat Polyclonal (4th Extracellular Domain) Antibody
Rat
ELISA, WB
Unconjugated
100 µl/$801
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (aa139-188) Antibody
Human
WB
Unconjugated
100 µl/$424
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (C-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal (aa135-184) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$717
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
5 ml/$538
DRD1 / Dopamine Receptor D1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
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