Human CD36

Mouse

Human (tested or 100% immunogen sequence identity)

IgM Monoclonal

SMØ

FITC. Also available Unconjugated.

Ammonium sulfate precipitation

Unmodified

Human tonsil and peripheral blood mononuclear cells.

Recognizes the CD36 antigen, an 88kD cell surface glycoprotein expressed by platelets and monocytes/macrophages and also by some microvascular endothelium and erythroid precursors. CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team. This clone is also reported to block interaction of oxidized low-density lipoprotein (OXLDL) with CD36. XXX recommend the use of MCA722XZ for this purpose.

• Flow Cytometry (1:1 - 1:5)
• Applications tested for the base form of this product only

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide, 1% BSA

Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P16671 NCBI: NM_000072 NP_000063.2