Bovine CD14

Mouse

Bovine (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

CC-G33

FITC. Also available Unconjugated.

Protein G purified

Unmodified

Partially purified polypeptides isolated from bovine leucocyte cell surface membrane.

Recognizes bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Clone CC-G33 cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14.

• Flow Cytometry
• Applications tested for the base form of this product only

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, 0.09% Sodium Azide, 1% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08571 NCBI: NM_000591 NP_000582.1