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Anti-CASP9 / Caspase 9 Antibody LS-C148247

Ordering

Wt. Vol. Conc. Price
- 50 µl - $335

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

CASP9 / Caspase 9 Antibody LS-C148247 Images

[click image for a larger image and more details]
Immunohistochemistry
Formalin-fixed, paraffin-embedded dog brain sections stained for cleaved Caspase-9 expression...
Immunohistochemistry
Formalin-fixed, paraffin-embedded human brain sections stained for cleaved Caspase-9 expression...
Immunohistochemistry
Formalin-fixed, paraffin-embedded dog brain sections stained for cleaved Caspase-9 expression...
 

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Rabbit Polyclonal to Human CASP9 / Caspase 9
Human, Mouse, Rat, Dog, Gerbil
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Human CASP9 / Caspase 9
Rabbit
Human, Mouse, Rat, Dog, Gerbil (tested or 100% immunogen sequence identity)
Polyclonal
Unpurified serum

Applications

IHC - Paraffin (1:1000 - 1:5000), IHC - Frozen, Western blot (1:1000 - 1:2000), Immunoprecipitation (1:50 - 1:200)

Specificity and Use

CASP9 / Caspase 9 antibody was raised against recombinant catalytically active human Caspase-9 protein was used as immunogen for this antibody.
Human CASP9 / Caspase 9

Packaging

Antiserum, 0.05% sodium azide
Store at 4°C, stable for 6 months. For long term storage, aliquot and store at -20°C.
For research use only.

About CASP9 / Caspase 9

P55211 NM_001229 NP_001220.2

CASP9 Antibody, APAF3 Antibody, CASPASE-9c Antibody, ICE-LAP6 Antibody, MCH6 Antibody, ICE-like apoptotic protease 6 Antibody, APAF-3 Antibody, Apoptotic protease Mch-6 Antibody, CASP-9 Antibody, Caspase 9 Antibody, Caspase-9 Antibody, PPP1R56 Antibody

Caspase 9 is a cysteine C14 endopeptidase that mediates oncogene and drug-induced apoptosis. It is activated upon binding to Apaf-1/cytochrome c and inhibited upon phosphorylation by the serine/ threonine kinase Akt. Activated caspase-9 cleaves downstream caspases such as Caspase-3, -6 and -7 initiating the caspase cascade. Like other caspases, Caspase-9 plays a critical role in mediating apoptosis during normal brain development.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed, paraffin-embedded dog brain sections stained for cleaved Caspase-9 expression using LS-C148247 antibody at 1:2000. A. Section from a dog brain 2 hr after reperfusion injury. B. Section from a dog brain sham control (brain surgery but no injury). Hematoxylin-Eos in counterstain.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed, paraffin-embedded human brain sections stained for cleaved Caspase-9 expression using LS-C148247 antibody at 1:2000. A. Section from a patient 24 hr after head trauma. B. Control: section from a patient with no known neurological disease or head injury. Hematoxylin-Eos in counterstain.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed, paraffin-embedded dog brain sections stained for cleaved Caspase-9 expression using LS-C148247 antibody at 1:2000. A and B. The pattern of Caspase-9 staining may vary between different types of neurons. Hematoxylin-Eosin counterstain.
 

Requested From: United States
Date Requested: 10/31/2014

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