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Anti-BAG3 / BAG-3 Antibody (C-Terminus) IHC-plus™ LS-B3925

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

BAG3 / BAG-3 Antibody LS-B3925 Images

[click image for a larger image and more details]
Immunohistochemistry
Anti-BAG3 antibody IHC of human skeletal muscle.
Immunohistochemistry
Anti-BAG3 antibody IHC of human heart.
Immunohistochemistry
Anti-BAG3 antibody IHC of human placenta.
 

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Goat Polyclonal to Human BAG3 / BAG-3
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human BAG3 / BAG-3
Goat
Human (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (3.75 µg/ml), Western blot, ELISA (1:8000)

Specificity and Use

BAG3 / BAG-3 antibody was raised against synthetic peptide C-SSMTDTPGNPAAP from the C-terminus of human BAG3 (NP_004272.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (85%), Monkey (85%), Marmoset (85%).
LS-E25374 - Lyophilized - 100 µg - $145.00
C-Terminus
Human BAG3.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About BAG3 / BAG-3

O95817 NM_004281 NP_004272.2

BAG3 Antibody, Bcl-2-associated athanogene 3 Antibody, Bcl-2-binding protein Bis Antibody, BCL2-binding athanogene 3 Antibody, BIS Antibody, BAG-3 Antibody, CAIR-1 Antibody, Docking protein cair1 Antibody, BCL2-associated athanogene 3 Antibody, Docking protein CAIR-1 Antibody

This protein has a number of names including Bis, CAIR-1, and BAG-3 and belongs to a family of proteins that share the BAG domain. BAG-3 binds to HSP-70 and inhibits Hsp-mediated proteasomal degradation by virtue of its C-terminal BAG domain that interacts with the ATP binding site of Hsp-70. This protein has also been shown to interact with Bcl-2 and by it self exerts weak anti-apoptotic activity but is synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.

Immunohistochemistry

Immunohistochemistry
Anti-BAG3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3925 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-BAG3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3925 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-BAG3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3925 concentration 3.75 ug/ml.
 

Requested From: United States
Date Requested: 10/25/2014

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