Human APP / Beta Amyloid Precursor

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

MAb1.1

Unconjugated

Protein G purified

Unmodified

aa37-42

Clone Mab1.1 recognizes Beta-amyloid protein 42 (also known as Abeta42), the 42 amino acid peptide processed from Amyloid precursor protein (APP). There are several forms of Abeta peptides processed from APP, the most common being Abeta40 and Abeta42. Amyloid plaques contain both Abeta40 and Abeta42. Abeta40 is more common, but Abeta42 more fibrillogenic and therefore associated with disease states such as Alzheimer's disease. Clone Mab1.1 specifically binds to the 37-42aa region, and does not recognize full-length APP or the 40 amino acid peptide processed from APP (Abeta40). It stains diffuse plaques found in the brain of Alzheimer's disease patients. It does not stain healthy brain tissue or other organs.

• IHC - Paraffin
• IHC - Frozen (20 - 40 µg/ml)
• ELISA (0.2 µg/ml)

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P05067 NCBI: NM_000484 NP_000475.1