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TRIP10 / CIP4 Antibodies

thyroid hormone receptor interactor 10

Gene Name: thyroid hormone receptor interactor 10
Synonyms: TRIP10 Antibody, Cdc42-interacting protein 4 Antibody, Protein Felic Antibody, Salt tolerator Antibody, STOT Antibody, STP Antibody, TR-interacting protein 10 Antibody, Salt tolerant protein Antibody, CIP4 Antibody, HSTP Antibody, TRIP-10 Antibody
Target Sequences: NM_004240 NP_004231.1 Q15642
 TRIP10 / CIP4 Feature Table

TRIP10 / CIP4 Antibodies (7)

Target Host Clonality Format Epitope Reactivity Applications
TRIP10 / CIP4 Rabbit Monoclonal Human, Mouse, Rat IHC-P, WB
TRIP10 / CIP4 Antibody [EPR1965] LS-C138031 Rabbit Monoclonal thumb(2)
100 µl - 385.00
Applications: IHC-P, WB Epitope:  
Reactivity: Hu, Mu, Rt Format: Unconjugated  
TRIP10 / CIP4 Rabbit Monoclonal Human, Mouse, Rat WB
TRIP10 / CIP4 Antibody [EPR1966(2)] LS-C138042 Rabbit Monoclonal thumb(1)
100 µl - 385.00
Applications: WB Epitope:  
Reactivity: Hu, Mu, Rt Format: Unconjugated  
TRIP10 / CIP4 Rabbit Polyclonal Human WB
TRIP10 / CIP4 Antibody LS-C160215 Rabbit Polyclonal thumb(1)
100 µg - 290.00
Applications: WB Epitope: aa114-145  
Reactivity: Hu Format: Unconjugated  
TRIP10 / CIP4 Rabbit Polyclonal Bovine, Dog, Human, Mouse, Rat, Xenopus WB
TRIP10 / CIP4 Antibody LS-C30012 Rabbit Polyclonal thumb(1)
50 µg - 380.00
Applications: WB Epitope: N-Terminus  
Reactivity: Bo, Do, Fr ... Format: Unconjugated  
TRIP10 / CIP4 Rabbit Polyclonal Bovine, Human, Mouse, Rat WB
TRIP10 / CIP4 Antibody LS-C109873 Rabbit Polyclonal thumb(1)
50 µg - 370.00
Applications: WB Epitope: N-Terminus  
Reactivity: Bo, Hu, Mu ... Format: Unconjugated  
TRIP10 / CIP4 Rabbit Polyclonal Bovine, Human, Mouse, Rabbit, Rat, Xenopus, Zebrafish WB
TRIP10 / CIP4 Antibody LS-C110274 Rabbit Polyclonal thumb(1)
50 µg - 370.00
Applications: WB Epitope: Internal  
Reactivity: Bo, Fr, Hu ... Format: Unconjugated  
TRIP10 / CIP4 Rabbit Polyclonal Human IP
TRIP10 / CIP4 Antibody LS-C76567 Rabbit Polyclonal
100 µg - 535.00
Applications: IP Epitope: aa25-75  
Reactivity: Hu Format: Unconjugated  

TRIP10 / CIP4 Feature Table


Feature Type Location Details
Function 1 - 601 Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Induction 1 - 601 Induced by adriamycin treatment and this effect is counteracted by HGF/SF. Expression is reduced during differentiation.
Modification 296 - 296 Phosphoserine
Modification 299 - 299 Phosphoserine
Modification 335 - 335 Phosphoserine
Modification 351 - 351 Phosphoserine
Molecular Weight 1 - 601 68352
Similarity 1 - 601 Belongs to the FNBP1 family.
Similarity 1 - 601 Contains 1 FCH domain.
Similarity 1 - 601 Contains 1 REM (Hr1) repeat.
Similarity 1 - 601 Contains 1 SH3 domain.
Subcellular Location 1 - 601 Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Note=Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9.
Subcellular Location 1 - 601 Isoform 5: Cytoplasm, perinuclear region.
Subunit 1 - 601 Interacts specifically with GTP-bound RHOQ. Interacts with DNM2 and PDE6G (By similarity). Interacts specifically with GTP-bound CDC42. Interacts with AKAP9, ARHGAP17, DAAM1, DIAPH1, DIAPH2, DNM1, FASLG/FASL, GAPVD1, LYN, microtubules, SRC, WAS/WASP and WASL/N-WASP. Interacts with the ligand binding domain of the thyroid receptor (TR) in the presence of thyroid hormone. May interact with CTNNB1 and HD/HTT.
Tissue Specificity 1 - 601 Expressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea.

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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