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TFDP2 / DP2 Antibodies

transcription factor Dp-2 (E2F dimerization partner 2)

Gene Name: transcription factor Dp-2 (E2F dimerization partner 2)
Synonyms: TFDP2 Antibody, DP2 Antibody, E2F dimerization partner 2 Antibody, Dp-2 Antibody, Transcription factor Dp-2 Antibody
Target Sequences: U18422 NP_006277.1 Q14188
 TFDP2 / DP2 Feature Table

TFDP2 / DP2 Antibodies (7)

Target Host Clonality Format Epitope Reactivity Applications
TFDP2 / DP2 Rabbit Polyclonal Mouse WB
TFDP2 / DP2 Antibody LS-C116128 Rabbit Polyclonal thumb(1)
50 µg - 380.00
Applications: WB Epitope: C-Terminus  
Reactivity: Mu Format: Unconjugated  
TFDP2 / DP2 Rabbit Polyclonal Bovine, Dog, Human, Mouse, Rat IHC, WB
TFDP2 / DP2 Antibody LS-C30921 Rabbit Polyclonal thumb(2)
100 µg - 335.00
Applications: IHC, WB Epitope: N-Terminus  
Reactivity: Bo, Do, Hu ... Format: Unconjugated  
TFDP2 / DP2 Rabbit Polyclonal Human, Rat WB
TFDP2 / DP2 Antibody LS-C170173 Rabbit Polyclonal thumb(1)
50 µg - 365.00
Applications: WB Epitope: N-Terminus  
Reactivity: Hu, Rt Format: Unconjugated  
TFDP2 / DP2 Rabbit Polyclonal Human, Mouse, Rat WB
TFDP2 / DP2 Antibody LS-C177245 Rabbit Polyclonal thumb(1)
100 µl - 345.00
Applications: WB Epitope: Asp113  
Reactivity: Hu, Mu, Rt Format: Unconjugated  
TFDP2 / DP2 Mouse Monoclonal Human DB
TFDP2 / DP2 Antibody [TFD5I455] LS-C184249 Mouse Monoclonal
50 µg - 335.00
Applications: DB Epitope:  
Reactivity: Hu Format:  
TFDP2 / DP2 Mouse Monoclonal Human GS
TFDP2 / DP2 Antibody LS-C64999 Mouse Monoclonal
100 µl - 465.00
Applications: GS Epitope:  
Reactivity: Hu Format: Unconjugated  
TFDP2 / DP2 Mouse Monoclonal Human WB
TFDP2 / DP2 Antibody LS-C76483 Mouse Monoclonal
50 µg - 430.00
Applications: WB Epitope:  
Reactivity: Hu Format: Unconjugated  

TFDP2 / DP2 Feature Table


Feature Type Location Details
Function 1 - 446 Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Modification 24 - 24 Phosphoserine
Modification 42 - 42 Phosphoserine
Molecular Weight 1 - 446 49236
Similarity 1 - 446 Belongs to the E2F/DP family.
Subcellular Location 1 - 446 Nucleus.
Subunit 1 - 446 Component of the DRTF1/E2F transcription factor complex. Forms heterodimers with E2F family members. The complex can interact with hypophosphorylated retinoblastoma protein RB1 and related proteins (RBL1 and RBL2) that inhibit the E2F transactivation domain. During the cell cycle, RB becomes phosphorylated in mid-to-late G1 phase, detaches from the DRTF1/E2F complex rendering E2F transcriptionally active. Viral oncoproteins, notably E1A, T-antigen and HPV E7, are capable of sequestering RB protein, thus releasing the active complex. Interacts with GMCL (By similarity). Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 fo
Tissue Specificity 1 - 446 High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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