STRADB / ALS2CR2 Antibodies

STE20-related kinase adaptor beta

ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1b converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.

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STRADB / ALS2CR2 Antibodies (16)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
STRADB / ALS2CR2	Goat	Polyclonal	Human	ELISA, IHC-P, WB	STRADB / ALS2CR2 Antibody LS-B2747 Goat Polyclonal (3) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Bovine, Chimpanzee, Dog, Horse, Human	IHC-P, WB	STRADB / ALS2CR2 Antibody LS-B7955 Rabbit Polyclonal (2) 50 µg - 385.00 Applications: IHC-P, WB Epitope: aa200-250   Reactivity: Bo, Ch, Do ... Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human, Mouse, Rat	IHC-P, WB	STRADB / ALS2CR2 Antibody LS-B178 Rabbit Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, WB Epitope: Internal   Reactivity: Hu, Mu, Rt Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	IHC, WB	STRADB / ALS2CR2 Antibody LS-C343 Rabbit Polyclonal (2) 100 µg - 350.00 500 µg - 1165.00 1000 µg - 2195.00 Applications: IHC, WB Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	IHC-P, WB	STRADB / ALS2CR2 Antibody LS-C121114 Rabbit Polyclonal 100 µg - 415.00 Applications: IHC-P, WB Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	WB	STRADB / ALS2CR2 Antibody LS-C156299 Rabbit Polyclonal (2) 100 µg - 290.00 Applications: WB Epitope: aa49-78   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Mouse	WB	STRADB / ALS2CR2 Antibody LS-C164584 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: aa389-418   Reactivity: Mu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	WB	STRADB / ALS2CR2 Antibody LS-C98094 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	WB	STRADB / ALS2CR2 Antibody LS-C98095 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	WB	STRADB / ALS2CR2 Antibody LS-C98096 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Mouse	ELISA, WB	STRADB / ALS2CR2 Antibody LS-C40717 Rabbit Polyclonal 100 µg - 245.00 Applications: WB, ELISA Epitope: aa399-418   Reactivity: Mu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Mouse	WB	STRADB / ALS2CR2 Antibody LS-C83394 Rabbit Polyclonal 100 µg - 354.00 Applications: WB Epitope:   Reactivity: Mu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Chimpanzee, Dog, Human, Macaque, Monkey	ELISA	STRADB / ALS2CR2 Antibody LS-C148958 Rabbit Polyclonal 100 µl - 260.00 Applications: ELISA Epitope: aa8-25   Reactivity: Ch, Do, Hu ... Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Mouse	WB	STRADB / ALS2CR2 Antibody LS-C2824 Rabbit Polyclonal 100 µg - 335.00 Applications: WB Epitope: aa399-418   Reactivity: Mu Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human, Mouse, Rat	WB	STRADB / ALS2CR2 Antibody LS-C24645 Rabbit Polyclonal 100 µg - 430.00 Applications: WB Epitope: Internal   Reactivity: Hu, Mu, Rt Format: Unconjugated
STRADB / ALS2CR2	Rabbit	Polyclonal	Human	WB	STRADB / ALS2CR2 Antibody LS-C24646 Rabbit Polyclonal 100 µg - 430.00 Applications: WB Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated

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STRADB / ALS2CR2 Feature Table

Feature Type	Location	Details
Function	1 - 418	Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.
Molecular Weight	1 - 418	47026
Similarity	1 - 418	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Similarity	1 - 418	Contains 1 protein kinase domain.
Subcellular Location	1 - 418	Nucleus. Cytoplasm.
Subunit	1 - 418	Interacts with BIRC4/XIAP. These two proteins are likely to coexist in a complex with TAK1, TRAF6, TAB1 and TAB2.
Tissue Specificity	1 - 418	Highly expressed in heart, skeletal muscle, testis, liver and colon.

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