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KDM5A / JARID1A Antibodies
lysine (K)-specific demethylase 5A
| Gene Name: |
lysine (K)-specific demethylase 5A |
| Synonyms: |
KDM5A Antibody, Histone demethylase JARID1A Antibody, JARID1A Antibody, RBBP-2 Antibody, RBBP2 Antibody, Lysine-specific demethylase 5A Antibody |
| Target Sequences: |
NM_005056
NP_005047.2
P29375
|
| | KDM5A / JARID1A Feature Table |
KDM5A / JARID1A Antibodies (4)
| Target |
Host |
Clonality |
Format |
Epitope |
Reactivity |
Applications |
| KDM5A / JARID1A |
Rabbit |
Polyclonal |
Human |
IHC, WB |
| KDM5A / JARID1A Antibody LS-C165352 |
Rabbit Polyclonal |
 (2)
|
|
| Applications: IHC, WB |
Epitope: aa1608-1641 |
|
| Reactivity: Hu |
Format: Unconjugated |
|
|
| KDM5A / JARID1A |
Rabbit |
Polyclonal |
Human |
ELISA, WB |
| KDM5A / JARID1A Antibody LS-C47126 |
Rabbit Polyclonal |
|
|
| Applications: WB, ELISA |
Epitope: C-Terminus |
|
| Reactivity: Hu |
Format: Unconjugated |
|
|
| KDM5A / JARID1A |
Rabbit |
Polyclonal |
Human |
ELISA |
| KDM5A / JARID1A Antibody LS-C148976 |
Rabbit Polyclonal |
|
|
| Applications: ELISA |
Epitope: aa1690-1703 |
|
| Reactivity: Hu |
Format: Unconjugated |
|
|
| KDM5A / JARID1A |
Rabbit |
Polyclonal |
Human, Mouse |
IP, WB |
| KDM5A / JARID1A Antibody LS-C71155 |
Rabbit Polyclonal |
|
|
| Applications: WB, IP |
Epitope: C-Terminus |
|
| Reactivity: Hu, Mu |
Format: Unconjugated |
|
|
KDM5A / JARID1A Feature Table
| Feature Type |
Location |
Details |
| Function |
1 - 1690 |
Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. |
| Modification |
1111 - 1111 |
Phosphoserine |
| Modification |
1331 - 1331 |
Phosphoserine |
| Modification |
1343 - 1343 |
Phosphothreonine |
| Modification |
1345 - 1345 |
Phosphoserine |
| Modification |
1598 - 1598 |
Phosphoserine |
| Modification |
1603 - 1603 |
Phosphoserine |
| Modification |
1666 - 1666 |
Phosphoserine |
| Molecular Weight |
1 - 1690 |
192095 |
| Similarity |
1 - 1690 |
Belongs to the JARID1 histone demethylase family. |
| Similarity |
1 - 1690 |
Contains 1 ARID domain. |
| Similarity |
1 - 1690 |
Contains 1 JmjC domain. |
| Similarity |
1 - 1690 |
Contains 1 JmjN domain. |
| Similarity |
1 - 1690 |
Contains 3 PHD-type zinc fingers. |
| Subcellular Location |
1 - 1690 |
Nucleus, nucleolus. Note=Occupies promoters of genes involved in RNA metabolism and mitochondrial function (By similarity). |
| Subunit |
1 - 1690 |
Interacts with SUZ12; the interaction is direct (By similarity). Interacts with the viral protein-binding domain of RB1. Interacts with ESR1, MYC, MYCN and LMO2. |
If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.
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