HP / Haptoglobin Antibodies

haptoglobin

The Haptoglobin (HP) gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in Haptoglobin and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

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HP / Haptoglobin Antibodies (35)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
HP / Haptoglobin	Rabbit	Polyclonal	Human	ELISA, IHC-P, WB	HP / Haptoglobin Antibody LS-B2266 Rabbit Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	HP / Haptoglobin Antibody [2F4] LS-B2863 Mouse Monoclonal (3) 50 µl - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	HP / Haptoglobin Antibody [26E11] LS-B7083 Mouse Monoclonal (2) 50 µl - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	ELISA, IF, IHC-P	HP / Haptoglobin Antibody LS-B32 Rabbit Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, IF, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human	ELISA, IHC-P	HP / Haptoglobin Antibody LS-B5968 Goat Polyclonal (2) 50 µg - 385.00 Applications: IHC-P, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	HP / Haptoglobin Antibody LS-B8034 Mouse Monoclonal (2) 50 µl - 385.00 Applications: IHC-P, WB, ELISA Epitope: aa19-406   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human	ELISA, IHC-P	HP / Haptoglobin Antibody LS-B6719 Goat Polyclonal (1) 250 µg - 385.00 Applications: IHC-P, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human	ELISA, WB	HP / Haptoglobin Antibody LS-C125698 Goat Polyclonal 1000 µg - 395.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	WB	HP / Haptoglobin Antibody LS-C110675 Rabbit Polyclonal (1) 50 µg - 370.00 Applications: WB Epitope: Internal   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	Flo, IF, IHC, WB	HP / Haptoglobin Antibody LS-C164994 Rabbit Polyclonal (5) 100 µg - 290.00 Applications: IHC, IF, WB... Epitope: aa299-326   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	IHC	HP / Haptoglobin Antibody LS-C177721 Rabbit Polyclonal (1) 100 µl - 345.00 Applications: IHC Epitope: Val328   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	IHC-P	HP / Haptoglobin Antibody LS-C185570 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: IHC-P Epitope: aa57-406   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	Flo, IF, WB	HP / Haptoglobin Antibody [4H5] LS-C115622 Mouse Monoclonal (4) 100 µl - 325.00 Applications: IF, WB, Flo Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	Flo, IF, WB	HP / Haptoglobin Antibody [4C2] LS-C115704 Mouse Monoclonal (3) 100 µl - 325.00 Applications: IF, WB, Flo Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	Flo, WB	HP / Haptoglobin Antibody [1B1] LS-C115623 Mouse Monoclonal (3) 100 µl - 325.00 Applications: WB, Flo Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	IF, WB	HP / Haptoglobin Antibody [6H2] LS-C115621 Mouse Monoclonal (2) 100 µl - 325.00 Applications: IF, WB Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Dog, Human, Porcine	ELISA, WB	HP / Haptoglobin Antibody LS-C154927 Goat Polyclonal (1) 100 µg - 360.00 Applications: WB, ELISA Epitope: Internal   Reactivity: Do, Hu, Po Format:
HP / Haptoglobin	Goat	Polyclonal	Human	ELISA, WB	HP / Haptoglobin Antibody LS-C154928 Goat Polyclonal (1) 100 µg - 360.00 Applications: WB, ELISA Epitope: Internal   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	WB	HP / Haptoglobin Antibody LS-C186286 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: WB Epitope: aa129-375   Reactivity: Hu Format:
HP / Haptoglobin	Rabbit	Polyclonal	Dog, Human, Mouse, Pig, Rabbit, Rat	WB	HP / Haptoglobin Antibody LS-C40372 Rabbit Polyclonal (1) 50 µg - 380.00 Applications: WB Epitope: N-Terminus   Reactivity: Do, Hu, Mu ... Format:
HP / Haptoglobin	Chicken	Polyclonal	Human	ELISA, WB	HP / Haptoglobin Antibody LS-C96141 Chicken Polyclonal 1000 µg - 365.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Sheep	Polyclonal	Cat, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat	ID	HP / Haptoglobin Antibody LS-C42319 Sheep Polyclonal 1000 µl - 265.00 Applications: ID Epitope:   Reactivity: Ca, Do, Ho ... Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	ELISA	HP / Haptoglobin Antibody [637400] LS-C84092 Mouse Monoclonal 100 µl - 475.00 Applications: ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Chicken	Polyclonal	Human	WB	HP / Haptoglobin Antibody LS-C96127 Chicken Polyclonal 100 µg - 365.00 Applications: WB Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human		HP / Haptoglobin Antibody LS-C85827 Goat Polyclonal 5000 µl - 320.00 Applications: Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Chicken	Polyclonal	Human, Mouse, Rat	ELISA, WB	HP / Haptoglobin Antibody LS-C24116 Chicken Polyclonal 50 µg - 455.00 Applications: WB, ELISA Epitope:   Reactivity: Hu, Mu, Rt Format:
HP / Haptoglobin	Goat	Polyclonal	Pig	ELISA, IE	HP / Haptoglobin Antibody LS-C185084 Goat Polyclonal 1000 µl - 395.00 Applications: ELISA, IE Epitope:   Reactivity: Po Format:
HP / Haptoglobin	Rabbit	Polyclonal	Human	ELISA	HP / Haptoglobin Antibody LS-C125699 Rabbit Polyclonal 1000 µg - 395.00 Applications: ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Sheep	Polyclonal	Human	ELISA	HP / Haptoglobin Antibody LS-C129541 Sheep Polyclonal 1000 µl - 385.00 Applications: ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Sheep	Polyclonal	Human	ELISA	HP / Haptoglobin Antibody LS-C129542 Sheep Polyclonal 1000 µl - 435.00 Applications: ELISA Epitope:   Reactivity: Hu Format: HRP
HP / Haptoglobin	Mouse	Monoclonal	Human	ELISA	HP / Haptoglobin Antibody LS-C24120 Mouse Monoclonal 100 µg - 550.00 Applications: ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Mouse	Monoclonal	Human	ELISA	HP / Haptoglobin Antibody LS-C24115 Mouse Monoclonal 100 µl - 320.00 Applications: ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human	ELISA	HP / Haptoglobin Antibody LS-C125697 Goat Polyclonal 1000 µl - 395.00 Applications: ELISA Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human		HP / Haptoglobin Antibody LS-C24111 Goat Polyclonal 5000 µl - 585.00 Applications: Epitope:   Reactivity: Hu Format:
HP / Haptoglobin	Goat	Polyclonal	Human		HP / Haptoglobin Antibody LS-C129545 Goat Polyclonal 1000 µl - 315.00 Applications: Epitope:   Reactivity: Hu Format:

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HP / Haptoglobin Feature Table

Feature Type	Location	Details
Function	1 - 406	Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
Molecular Weight	1 - 406	45205
Similarity	1 - 406	Belongs to the peptidase S1 family.
Similarity	1 - 406	Contains 1 peptidase S1 domain.
Similarity	1 - 406	Contains 2 Sushi (CCP/SCR) domains.
Subcellular Location	1 - 406	Secreted.
Subunit	1 - 406	Tetramer of two alpha and two beta chains.
Tissue Specificity	1 - 406	Expressed by the liver and secreted in plasma.

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