HIF1A / HIF1 Alpha Antibodies

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). HIF1A encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas.

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HIF1A / HIF1 Alpha Antibodies (133)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-B495 Rabbit Polyclonal (1) 100 µl - 385.00 Applications: IHC-P, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Guinea pig, Human, Mouse, Primate, Rat	IHC, IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-B2823 Rabbit Polyclonal (3) 100 µl - 385.00 Applications: IHC, IHC-P, WB... Epitope: aa432-528   Reactivity: Gp, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Mouse, Pig	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-B674 Rabbit Polyclonal (2) 100 µl - 385.00 Applications: IHC-P, WB Epitope: aa432-528   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep	IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-B110 Mouse Monoclonal (1) 50 µl - 385.00 Applications: IHC-P, WB, IP Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse	IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-B4816 Rabbit Polyclonal (2) 50 µl - 385.00 Applications: IHC-P, WB, IP Epitope: aa609-826   Reactivity: Hu, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Monkey, Mouse	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-B1503 Rabbit Polyclonal (2) 125 µl - 385.00 Applications: IHC-P, WB Epitope: C-Terminus   Reactivity: Hu, Mo, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Dog, Human, Mouse, Rat	ICC, IF, IHC-P	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-B109 Mouse Monoclonal (1) 50 µl - 385.00 Applications: IHC-P, ICC, IF Epitope: aa329-530   Reactivity: Bo, Do, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Chicken, Human, Mouse, Pig, Rabbit, Rat, Xenopus	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-B5879 Rabbit Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, WB Epitope: N-Terminus   Reactivity: Bo, Ck, Fr ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	IHC-P, WB	HIF1A / HIF1 Alpha Antibody [HA111] LS-B145 Mouse Monoclonal (1) 100 µl - 385.00 Applications: IHC-P, WB Epitope: aa329-530   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Rat	IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-B6182 Rabbit Polyclonal (1) 50 µl - 385.00 Applications: IHC-P, WB, IP Epitope:   Reactivity: Hu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse	Flo, IF, IHC, WB	HIF1A / HIF1 Alpha Antibody LS-C166867 Rabbit Polyclonal (4) 100 µg - 290.00 Applications: IHC, IF, WB... Epitope: aa520-550   Reactivity: Hu, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Monoclonal	Human, Rat	ICC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [EP1215Y] LS-C49968 Rabbit Monoclonal (2) 100 µl - 415.00 Applications: IHC-P, ICC, WB Epitope: C-Terminus   Reactivity: Hu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC, WB	HIF1A / HIF1 Alpha Antibody LS-C83732 Rabbit Polyclonal 100 µl - 335.00 Applications: IHC, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Monkey, Mouse	ELISA, ICC, IHC, WB	HIF1A / HIF1 Alpha Antibody [1A3] LS-C169345 Mouse Monoclonal (5) 100 µl - 350.00 Applications: IHC, ICC, WB... Epitope:   Reactivity: Hu, Mo, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep	IF, IHC, IHC-Fr, IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140776 Mouse Monoclonal (1) 250 µl - 330.00 Applications: IHC, IHC-Fr, IF... Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: Biotin
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C83705 Mouse Monoclonal (4) 100 µl - 335.00 Applications: IHC, WB Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Monkey, Mouse	ELISA, IHC, WB	HIF1A / HIF1 Alpha Antibody [1A3] LS-C171583 Mouse Monoclonal (3) 100 µl - 365.00 Applications: IHC, WB, ELISA Epitope:   Reactivity: Hu, Mo, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Hamster, Human	IF, IHC, WB	HIF1A / HIF1 Alpha Antibody LS-C166866 Rabbit Polyclonal (3) 100 µg - 290.00 Applications: IHC, IF, WB Epitope: aa1-31   Reactivity: Ha, Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	Flo, IHC, WB	HIF1A / HIF1 Alpha Antibody LS-C166864 Rabbit Polyclonal (3) 100 µg - 290.00 Applications: IHC, WB, Flo Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Dog, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C2557 Mouse Monoclonal (2) 100 µl - 335.00 Applications: IHC, WB, IP Epitope: aa432-528   Reactivity: Bo, Do, Fe ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, WB	HIF1A / HIF1 Alpha Antibody LS-C177574 Rabbit Polyclonal (2) 100 µl - 345.00 Applications: IHC, WB Epitope: Lys377   Reactivity: Hu, Mu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ICC, IF, IHC, IP	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C83706 Mouse Monoclonal (1) 100 µl - 335.00 Applications: IHC, ICC, IF... Epitope: aa329-530   Reactivity: Bo, Hu, Mu ... Format: Biotin
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ICC, IF, IHC, IHC-Fr, IHC-P, IP	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C140822 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, IHC-Fr... Epitope: aa329-530   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ICC, IF, IHC, IHC-Fr, IHC-P, IP	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C140823 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, IHC-Fr... Epitope: aa329-530   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ICC, IF, IHC, IHC-Fr, IHC-P, IP	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C140824 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, IHC-Fr... Epitope: aa329-530   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ELISA, ICC, IF, IHC-Fr, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C150386 Mouse Monoclonal 25 µg - 175.00 Applications: IHC-Fr, IHC-P, ICC... Epitope:   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep	IF, IHC, IHC-Fr, IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140777 Mouse Monoclonal 250 µl - 330.00 Applications: IHC, IHC-Fr, IF... Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: DY650
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep	IF, IHC, IHC-Fr, IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140778 Mouse Monoclonal 250 µl - 330.00 Applications: IHC, IHC-Fr, IF... Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: DY488
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep	IF, IHC, IHC-Fr, IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140780 Mouse Monoclonal 250 µl - 330.00 Applications: IHC, IHC-Fr, IF... Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: DY550
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ICC, IHC-Fr, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C153079 Mouse Monoclonal 100 µg - 335.00 Applications: IHC-Fr, IHC-P, ICC... Epitope:   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-C141170 Rabbit Polyclonal 100 µl - 330.00 Applications: IHC, IHC-P, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: DY650
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140802 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, WB Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: Biotin
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140803 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, WB Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140804 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, WB Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140805 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, WB Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: HiLyte Fluor, HiLyte Fluor 488
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rat, Sheep	IHC, IHC-P, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140806 Mouse Monoclonal 100 µl - 330.00 Applications: IHC, IHC-P, WB Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Mouse, Rat	IHC-Fr, IHC-P	HIF1A / HIF1 Alpha Antibody LS-C7465 Mouse Monoclonal 100 µl - 460.00 Applications: IHC-Fr, IHC-P Epitope: aa329-530   Reactivity: Hu, Mu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	IHC	HIF1A / HIF1 Alpha Antibody LS-C96684 Rabbit Polyclonal (2) 100 µg - 290.00 Applications: IHC Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Guinea pig, Human, Mouse, Pig, Primate, Rat	GS, ICC, IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C181014 Rabbit Polyclonal 100 µl - 365.00 Applications: IHC-P, ICC, WB... Epitope:   Reactivity: Gp, Hu, Mu ... Format: DY550
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Guinea pig, Human, Mouse, Pig, Primate, Rat	GS, ICC, IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C181016 Rabbit Polyclonal 100 µl - 365.00 Applications: IHC-P, ICC, WB... Epitope:   Reactivity: Gp, Hu, Mu ... Format: Biotin
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Guinea pig, Human, Mouse, Pig, Primate, Rat	GS, ICC, IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C181017 Rabbit Polyclonal 100 µl - 365.00 Applications: IHC-P, ICC, WB... Epitope:   Reactivity: Gp, Hu, Mu ... Format: DY650
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Guinea pig, Human, Mouse, Pig, Primate, Rat	GS, ICC, IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C181018 Rabbit Polyclonal 100 µl - 365.00 Applications: IHC-P, ICC, WB... Epitope:   Reactivity: Gp, Hu, Mu ... Format: DY488
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Guinea pig, Human, Mouse, Pig, Primate, Rat	GS, ICC, IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C181019 Rabbit Polyclonal 100 µl - 365.00 Applications: IHC-P, ICC, WB... Epitope:   Reactivity: Gp, Hu, Mu ... Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat, Sheep	IHC, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C26700 Mouse Monoclonal 100 µg - 470.00 Applications: IHC, WB, IP Epitope: aa432-528   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-C141171 Rabbit Polyclonal 100 µl - 330.00 Applications: IHC-P, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: DY488
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-C141172 Rabbit Polyclonal 100 µl - 330.00 Applications: IHC-P, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: DY550
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Ferret, Human, Mouse, Rat, Sheep	IHC-P	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C87583 Mouse Monoclonal 20 µg - 270.00 100 µg - 435.00 1 ml - 620.00 Applications: IHC-P Epitope:   Reactivity: Fe, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Ferret, Human, Mouse, Rat, Sheep	IHC-P	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C87584 Mouse Monoclonal 100 µg - 465.00 200 µg - 665.00 Applications: IHC-P Epitope:   Reactivity: Fe, Hu, Mu ... Format: Azide-free
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse	IHC, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C7453 Rabbit Polyclonal 50 µg - 422.00 Applications: IHC, WB, IP Epitope: aa609-826   Reactivity: Hu, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Pig, Rat, Sheep	IHC-P, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C7464 Mouse Monoclonal 100 µl - 460.00 Applications: IHC-P, WB, IP Epitope: aa432-528   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C123751 Rabbit Polyclonal 100 µg - 395.00 Applications: IHC, WB, IP Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Monkey, Mouse	Flo, IHC, WB	HIF1A / HIF1 Alpha Antibody LS-C123797 Rabbit Polyclonal 20 µg - 465.00 Applications: IHC, WB, Flo Epitope: C-Terminus   Reactivity: Hu, Mo, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-C121233 Rabbit Polyclonal 100 µl - 445.00 Applications: IHC-P, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: HRP
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Primate, Rat	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-C121234 Rabbit Polyclonal 100 µg - 445.00 Applications: IHC-P, WB Epitope: aa530-825   Reactivity: Hu, Mu, Pr ... Format: Biotin
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Rabbit, Rat	IHC-P, WB	HIF1A / HIF1 Alpha Antibody LS-C121964 Rabbit Polyclonal 100 µg - 440.00 Applications: IHC-P, WB Epitope: aa775-790   Reactivity: Hu, Mu, Rb ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	Flo, IF, WB	HIF1A / HIF1 Alpha Antibody LS-C166865 Rabbit Polyclonal (3) 100 µg - 290.00 Applications: IF, WB, Flo Epitope: aa710-740   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	DB, Flo	HIF1A / HIF1 Alpha Antibody LS-C165096 Rabbit Polyclonal (2) 100 µg - 290.00 Applications: Flo, DB Epitope: aa547-577   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Dog, Human, Monkey, Mouse, Rat, Xenopus	ELISA, WB	HIF1A / HIF1 Alpha Antibody LS-C59282 Rabbit Polyclonal (1) 100 µl - 350.00 Applications: WB, ELISA Epitope: Hydroxy-Pro564   Reactivity: Bo, Do, Fr ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Mouse, Pig, Primate, Rabbit, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C83866 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: WB Epitope: aa400-550   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C110238 Rabbit Polyclonal (1) 50 µg - 370.00 Applications: WB Epitope: Internal   Reactivity: Bo, Ck, Do ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C134910 Rabbit Polyclonal (1) 50 µg - 380.00 Applications: WB Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C171749 Rabbit Polyclonal (1) 100 µg - 260.00 Applications: WB Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C157806 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: aa735-762   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C159833 Mouse Monoclonal (1) 100 µl - 290.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Mouse, Pig, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C143395 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: WB Epitope: Exon 12   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Chicken, Human, Mouse, Primate, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C143401 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: WB Epitope: Exon 13   Reactivity: Bo, Ck, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Mouse, Pig, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C143383 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: WB Epitope: Exon 9   Reactivity: Bo, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Pig	WB	HIF1A / HIF1 Alpha Antibody LS-C143389 Rabbit Polyclonal (1) 100 µl - 335.00 Applications: WB Epitope: Exon 10   Reactivity: Bo, Hu, Po Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Human, Mouse, Rat	ICC, IF, IP	HIF1A / HIF1 Alpha Antibody [ESEE122] LS-C83707 Mouse Monoclonal 100 µl - 335.00 Applications: ICC, IF, IP Epitope: aa329-530   Reactivity: Bo, Hu, Mu ... Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	GS, IF, IP	HIF1A / HIF1 Alpha Antibody LS-C26699 Mouse Monoclonal 100 µg - 470.00 Applications: IF, IP, GS Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	GS, IF	HIF1A / HIF1 Alpha Antibody [SPM404] LS-C33869 Mouse Monoclonal 50 µg - 295.00 Applications: IF, GS Epitope: aa530-826   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	GS, IF	HIF1A / HIF1 Alpha Antibody [OZ12] LS-C88380 Mouse Monoclonal 20 µg - 250.00 0.5 ml - 425.00 200 µg - 560.00 Applications: IF, GS Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	GS, IF	HIF1A / HIF1 Alpha Antibody [OZ12] LS-C88381 Mouse Monoclonal 100 µg - 455.00 200 µg - 595.00 Applications: IF, GS Epitope:   Reactivity: Hu Format: Azide-free
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Bovine, Ferret, Human, Mouse, Pig, Primate, Rabbit, Rat, Sheep	IP, WB	HIF1A / HIF1 Alpha Antibody [H1alpha67] LS-C140779 Mouse Monoclonal 250 µl - 330.00 Applications: WB, IP Epitope: aa432-528   Reactivity: Bo, Fe, Hu ... Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [HA111] LS-C141084 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa329-530   Reactivity: Hu Format: Biotin
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [HA111] LS-C141085 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa329-530   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [HA111] LS-C141086 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa329-530   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [HA111] LS-C141087 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa329-530   Reactivity: Hu Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [H1alpha 67-7] LS-C140817 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Hu Format: Biotin
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [H1alpha 67-7] LS-C140818 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [H1alpha 67-7] LS-C140819 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [H1alpha 67-7] LS-C140820 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Hu Format: HRP
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [H1alpha 67-7] LS-C140821 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody [HA111] LS-C140760 Mouse Monoclonal 100 µl - 330.00 Applications: WB Epitope: aa329-530   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C94217 Rabbit Polyclonal 500 µg - 343.00 Applications: WB Epitope: Internal   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Primate	WB	HIF1A / HIF1 Alpha Antibody [H1alpha 67-7] LS-C2554 Mouse Monoclonal 100 µl - 335.00 Applications: WB Epitope: aa432-528   Reactivity: Hu, Pr Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143390 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-450   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143391 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-450   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143392 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-450   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143393 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-450   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143394 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-450   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143384 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa350-400   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143385 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa350-400   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143386 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa350-400   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143387 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa350-400   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143388 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa350-400   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Pig	WB	HIF1A / HIF1 Alpha Antibody LS-C141259 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Bo, Hu, Po Format: Biotin
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Pig	WB	HIF1A / HIF1 Alpha Antibody LS-C141260 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Bo, Hu, Po Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Pig	WB	HIF1A / HIF1 Alpha Antibody LS-C141261 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Bo, Hu, Po Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Pig	WB	HIF1A / HIF1 Alpha Antibody LS-C141262 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Bo, Hu, Po Format: HRP
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Human, Pig	WB	HIF1A / HIF1 Alpha Antibody LS-C141263 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa432-528   Reactivity: Bo, Hu, Po Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Primate, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C142696 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-550   Reactivity: Bo, Do, Hu ... Format: Biotin
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Primate, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C142697 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-550   Reactivity: Bo, Do, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Primate, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C142698 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-550   Reactivity: Bo, Do, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Primate, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C142699 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-550   Reactivity: Bo, Do, Hu ... Format: HRP
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Primate, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C142700 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa400-550   Reactivity: Bo, Do, Hu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143402 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa700-750   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143403 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa700-750   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143404 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa700-750   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143405 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa700-750   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143406 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa700-750   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143396 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa550-600   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143397 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa550-600   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143398 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa550-600   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143399 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa550-600   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C143400 Rabbit Polyclonal 100 µl - 330.00 Applications: WB Epitope: aa550-600   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C144839 Rabbit Polyclonal 100 µl - 355.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C144840 Rabbit Polyclonal 100 µl - 355.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Rat	IP	HIF1A / HIF1 Alpha Antibody LS-C171750 Rabbit Polyclonal 100 µg - 325.00 Applications: IP Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Magnetic beads
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Mouse, Rat	IP	HIF1A / HIF1 Alpha Antibody LS-C171751 Rabbit Polyclonal 100 µg - 325.00 Applications: IP Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Sepharose
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human		HIF1A / HIF1 Alpha Antibody [OZ12] LS-C95509 Mouse Monoclonal 0.5 ml - 315.00 1 ml - 420.00 Applications: Epitope: aa530-826   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Mouse	GS, ICC, IP, WB	HIF1A / HIF1 Alpha Antibody LS-C7454 Mouse Monoclonal 100 µl - 580.00 Applications: ICC, WB, IP... Epitope: aa530-826   Reactivity: Hu, Mu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	GS, IF, WB	HIF1A / HIF1 Alpha Antibody LS-C7457 Mouse Monoclonal 250 µl - 330.00 Applications: IF, WB, GS Epitope: aa530-826   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Ferret, Human, Mouse, Rat, Sheep	IP, WB	HIF1A / HIF1 Alpha Antibody LS-C7469 Mouse Monoclonal 100 µg - 455.00 Applications: WB, IP Epitope: aa432-528   Reactivity: Fe, Hu, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Mouse, Rat, Sheep	ELISA, WB	HIF1A / HIF1 Alpha Antibody LS-C36834 Mouse Monoclonal 50 µg - 450.00 Applications: WB, ELISA Epitope: aa432-528   Reactivity: Hu, Mu, Rt ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	ELISA, WB	HIF1A / HIF1 Alpha Antibody LS-C36835 Mouse Monoclonal 100 µg - 550.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	ELISA, WB	HIF1A / HIF1 Alpha Antibody LS-C36836 Mouse Monoclonal 100 µg - 550.00 Applications: WB, ELISA Epitope: aa530-826   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	GS, IF	HIF1A / HIF1 Alpha Antibody LS-C124955 Mouse Monoclonal 500 µl - 480.00 Applications: IF, GS Epitope: aa530-826   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human, Rat	WB	HIF1A / HIF1 Alpha Antibody LS-C124956 Rabbit Polyclonal 100 µl - 425.00 Applications: WB Epitope: aa432-528   Reactivity: Hu, Rt Format: Unconjugated
HIF1A / HIF1 Alpha	Rabbit	Polyclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C124952 Rabbit Polyclonal 100 µl - 425.00 Applications: WB Epitope: aa400-550   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C124953 Mouse Monoclonal 100 µl - 420.00 Applications: WB Epitope: aa432-528   Reactivity: Hu Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human, Monkey, Mouse, Rat, Sheep	WB	HIF1A / HIF1 Alpha Antibody LS-C7463 Mouse Monoclonal 250 µl - 460.00 Applications: WB Epitope: aa432-528   Reactivity: Hu, Mo, Mu ... Format: Unconjugated
HIF1A / HIF1 Alpha	Mouse	Monoclonal	Human	WB	HIF1A / HIF1 Alpha Antibody LS-C7455 Mouse Monoclonal 100 µg - 445.00 Applications: WB Epitope: aa329-530   Reactivity: Hu Format: Unconjugated

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HIF1A / HIF1 Alpha Feature Table

Feature Type	Location	Details
Function	1 - 826	Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBPB and EP300. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP.
Induction	1 - 826	Under reduced oxygen tension. Induced also by various receptor-mediated factors such as growth factors, cytokines, and circulatory factors such as PDGF, EGF FGF-2 FGF-2 IGF-2, TGF-1 beta, HGF, TNF alpha, IL-1 beta, angiotensin-2 and thrombin. However, this induction is less intense than that stimulated by hypoxia.
Modification	402 - 402	4-hydroxyproline
Modification	564 - 564	4-hydroxyproline
Modification	800 - 800	S-nitrosocysteine (Probable)
Modification	803 - 803	(3S)-3-hydroxyasparagine
Molecular Weight	1 - 826	92670
Similarity	1 - 826	Contains 1 basic helix-loop-helix (bHLH) domain.
Similarity	1 - 826	Contains 1 PAC (PAS-associated C-terminal) domain.
Similarity	1 - 826	Contains 2 PAS (PER-ARNT-SIM) domains.
Subcellular Location	1 - 826	Cytoplasm. Nucleus. Note=Cytoplasmic in normoxia, nuclear translocation in response to hypoxia. Colocalizes with SUMO1 in the nucleus, under hypoxia.
Subunit	1 - 826	Interacts with the HIF1A beta/ARNT subunit; heterodimerization is required for DNA binding. Interacts with COPS5; the interaction increases the transcriptional activity of HIF1A through increased stability (By similarity). Interacts with CREBBP and EP300 (via TAZ-type 1 domains). Interacts with NCOA1, NCOA2, APEX and HSP90. Interacts (hydroxylated within the ODD domain) with VHLL (via beta domain); the interaction, leads to polyubiquitination and subsequent HIF1A proteasomal degradation. During hypoxia, sumoylated HIF1A also binds VHL; the interaction promotes the ubiquitination of HIF1A. Interacts with SENP1; the interaction desumoylates HIF1A resulting in stabilization and activation of transcription. Interacts (Via the ODD domain) with ARD1A; the interaction appears not to acetylate HIF1A nor have any affect on protein stability, during hypoxia. Interacts with RWDD3; the int
Tissue Specificity	1 - 826	Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors.

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