FOS / c-FOS Antibodies

FBJ murine osteosarcoma viral oncogene homolog

C-Fos is the product of an immediate early gene. It is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. The Fos and Jun proteins from dimeric complexes that stimulate transcription of genes containing AP-1 regulatory elements. Studies in rodents have shown that c-Fos is essential in regulating neuronal cell survival versus death. c-Fos is induced by neuronal activity, regulates the expression of the kainic acid receptor GLUR6 and brain derived neurotrophic factor (BDNF).

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FOS / c-FOS Antibodies (44)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	FOS / c-FOS Antibody [2D12] LS-B6419 Mouse Monoclonal (2) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	FOS / c-FOS Antibody [1H8] LS-B6420 Mouse Monoclonal (2) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	FOS / c-FOS Antibody [4E11] LS-B6421 Mouse Monoclonal (2) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, IHC-P, WB	FOS / c-FOS Antibody LS-B7018 Rabbit Polyclonal (2) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope: N-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, IHC-P, WB	FOS / c-FOS Antibody LS-B7309 Rabbit Polyclonal (2) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope: Internal   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, IHC-P, WB	FOS / c-FOS Antibody [2F3] LS-B6403 Mouse Monoclonal (1) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	ICC, IHC-Fr, IHC-P, IP, WB	FOS / c-FOS Antibody LS-C4263 Rabbit Polyclonal 100 µg - 475.00 Applications: IHC-Fr, IHC-P, ICC... Epitope: aa4-17   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Sheep	Polyclonal	Human, Rat	IF, IHC-Fr, IHC-P, WB	FOS / c-FOS Antibody LS-C4270 Sheep Polyclonal 500 µg - 465.00 Applications: IHC-Fr, IHC-P, IF... Epitope: aa4-17   Reactivity: Hu, Rt Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human, Mouse, Rat	IF, WB	FOS / c-FOS Antibody [2G9C3] LS-C77393 Mouse Monoclonal 100 µg - 515.00 Applications: IF, WB Epitope: Internal   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, Flo, IHC, WB	FOS / c-FOS Antibody [2G2] LS-C169074 Mouse Monoclonal (6) 100 µl - 350.00 Applications: IHC, WB, Flo... Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, WB	FOS / c-FOS Antibody LS-C176026 Rabbit Polyclonal (2) 100 µl - 345.00 Applications: IHC, WB Epitope: Phe3   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, WB	FOS / c-FOS Antibody LS-C177796 Rabbit Polyclonal (2) 100 µl - 345.00 Applications: IHC, WB Epitope: Ser368   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human	IHC	FOS / c-FOS Antibody LS-C50708 Rabbit Polyclonal (1) 50 µg - 355.00 Applications: IHC Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human	IHC, IP, WB	FOS / c-FOS Antibody LS-C51701 Rabbit Polyclonal 50 µg - 350.00 Applications: IHC, WB, IP Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human	ELISA, IHC, WB	FOS / c-FOS Antibody LS-C153598 Rabbit Polyclonal 100 µg - 310.00 Applications: IHC, WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human	IHC, WB	FOS / c-FOS Antibody LS-C144577 Rabbit Polyclonal 100 µl - 355.00 Applications: IHC, WB Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human	GS, IHC, WB	FOS / c-FOS Antibody LS-C66276 Rabbit Polyclonal 200 µl - 520.00 Applications: IHC, WB, GS Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human	Flo, WB	FOS / c-FOS Antibody LS-C99318 Rabbit Polyclonal (2) 100 µg - 290.00 Applications: WB, Flo Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, WB	FOS / c-FOS Antibody LS-C118358 Rabbit Polyclonal (1) 100 µg - 295.00 Applications: WB, ELISA Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Monoclonal	Human, Mouse, Rat	Flo, WB	FOS / c-FOS Antibody [EPR883(2)] LS-C138395 Rabbit Monoclonal (1) 100 µl - 385.00 Applications: WB, Flo Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	DB, ICC	FOS / c-FOS Antibody [554C1a] LS-C184425 Mouse Monoclonal (1) 50 µg - 335.00 Applications: ICC, DB Epitope:   Reactivity: Hu Format:
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	WB	FOS / c-FOS Antibody LS-C172113 Rabbit Polyclonal (1) 100 µg - 260.00 Applications: WB Epitope: Internal   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	WB	FOS / c-FOS Antibody LS-C140559 Rabbit Polyclonal (1) 10 blot - 525.00 Applications: WB Epitope: pThr325   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Bovine, Chicken, Dog, Human, Mouse, Pig, Rat	WB	FOS / c-FOS Antibody LS-C30908 Rabbit Polyclonal (1) 100 µg - 335.00 Applications: WB Epitope: C-Terminus   Reactivity: Bo, Ck, Do ... Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Rat	WB	FOS / c-FOS Antibody LS-C109677 Rabbit Polyclonal (1) 50 µg - 370.00 Applications: WB Epitope: Internal   Reactivity: Bo, Do, Hu ... Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Rat	WB	FOS / c-FOS Antibody LS-C112301 Rabbit Polyclonal (1) 50 µg - 370.00 Applications: WB Epitope: N-Terminus   Reactivity: Bo, Do, Hu ... Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Bovine, Dog, Human, Mouse, Pig, Rat	WB	FOS / c-FOS Antibody LS-C112334 Rabbit Polyclonal (1) 50 µg - 370.00 Applications: WB Epitope: Internal   Reactivity: Bo, Do, Hu ... Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human		FOS / c-FOS Antibody LS-C97021 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: Epitope: pThr232   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, WB	FOS / c-FOS Antibody [2C9] LS-C139156 Mouse Monoclonal 100 µg - 340.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	ELISA, WB	FOS / c-FOS Antibody [4D5] LS-C139157 Mouse Monoclonal 100 µg - 340.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Sheep	Polyclonal	Human, Mouse, Rat	WB	FOS / c-FOS Antibody LS-C93966 Sheep Polyclonal 500 µg - 293.00 Applications: WB Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	IP	FOS / c-FOS Antibody LS-C172114 Rabbit Polyclonal 100 µg - 325.00 Applications: IP Epitope: Internal   Reactivity: Hu, Mu, Rt Format: Sepharose
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse	ICC, IP, WB	FOS / c-FOS Antibody LS-C6879 Rabbit Polyclonal 100 µg - 455.00 Applications: ICC, WB, IP Epitope: aa75-155   Reactivity: Hu, Mu Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Dog, Human	ELISA, ICC, WB	FOS / c-FOS Antibody LS-C4266 Mouse Monoclonal 100 µg - 575.00 Applications: ICC, WB, ELISA Epitope: pSer374   Reactivity: Do, Hu Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Dog, Human, Mouse, Rat	ELISA, WB	FOS / c-FOS Antibody LS-C4265 Mouse Monoclonal 50 µg - 460.00 Applications: WB, ELISA Epitope: N-Terminus   Reactivity: Do, Hu, Mu ... Format: Unconjugated
FOS / c-FOS	Sheep	Polyclonal	Human, Rat	ICC, WB	FOS / c-FOS Antibody LS-C4257 Sheep Polyclonal 100 µg - 465.00 Applications: ICC, WB Epitope:   Reactivity: Hu, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Bovine, Cat, Pig	WB	FOS / c-FOS Antibody LS-C4262 Rabbit Polyclonal 50 µg - 425.00 Applications: WB Epitope: C-Terminus   Reactivity: Bo, Ca, Po Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Mouse	WB	FOS / c-FOS Antibody LS-C4264 Rabbit Polyclonal 200 µg - 580.00 Applications: WB Epitope: aa4-17   Reactivity: Mu Format: Unconjugated
FOS / c-FOS	Sheep	Polyclonal	Human	ELISA	FOS / c-FOS Antibody LS-C4272 Sheep Polyclonal 500 µg - 430.00 Applications: ELISA Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	WB	FOS / c-FOS Antibody LS-C6880 Rabbit Polyclonal 100 µl - 495.00 Applications: WB Epitope: pThr232   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Mouse	Monoclonal	Human	WB	FOS / c-FOS Antibody LS-C66275 Mouse Monoclonal 50 µg - 430.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
FOS / c-FOS	Chicken	Polyclonal	Human, Mouse, Rat	WB	FOS / c-FOS Antibody LS-C77392 Chicken Polyclonal 50 µg - 595.00 Applications: WB Epitope: aa168-380   Reactivity: Hu, Mu, Rt Format: Unconjugated
FOS / c-FOS	Sheep	Polyclonal	Human, Rabbit, Rat	ELISA	FOS / c-FOS Antibody LS-C77403 Sheep Polyclonal 50 µg - 430.00 Applications: ELISA Epitope: aa2-17   Reactivity: Hu, Rb, Rt Format: Unconjugated
FOS / c-FOS	Rabbit	Polyclonal	Human, Mouse, Rat	WB	FOS / c-FOS Antibody LS-C129153 Rabbit Polyclonal 100 µg - 395.00 Applications: WB Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated

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FOS / c-FOS Feature Table

Feature Type	Location	Details
Function	1 - 380	Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Modification	232 - 232	Phosphothreonine (By similarity)
Modification	325 - 325	Phosphothreonine (By similarity)
Modification	331 - 331	Phosphothreonine (By similarity)
Modification	362 - 362	Phosphoserine; by MAPK and RPS6KA3
Modification	374 - 374	Phosphoserine; by MAPK
Molecular Weight	1 - 380	40695
Similarity	1 - 380	Belongs to the bZIP family. Fos subfamily.
Similarity	1 - 380	Contains 1 bZIP domain.
Subcellular Location	1 - 380	Nucleus.
Subunit	1 - 380	Heterodimer with JUN. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB (By similarity).

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