Unfortunately, the antibody LS-C21299 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.

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Caspase 4 Antibodies

caspase 4, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease. The rodent homolog is known as Caspase 4 and Caspase 11.

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Caspase 4 Antibodies (30)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
Caspase 4	Rabbit	Polyclonal	Human, Mouse	IHC-P, WB	Caspase 4 Antibody LS-B710 Rabbit Polyclonal (3) 50 µg - 385.00 Applications: IHC-P, WB Epitope:   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	IHC-P, WB	Caspase 4 Antibody LS-B3793 Rabbit Polyclonal (3) 50 µg - 385.00 Applications: IHC-P, WB Epitope: Internal   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse	IHC, IHC-P, WB	Caspase 4 Antibody LS-B3789 Rabbit Polyclonal (2) 50 µg - 385.00 Applications: IHC, IHC-P, WB Epitope: N-Terminus   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Chicken	Polyclonal	Human	IHC-P, WB	Caspase 4 Antibody LS-B728 Chicken Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, WB Epitope: aa1-89   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse	IHC-P, WB	Caspase 4 Antibody LS-B6645 Rabbit Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, WB Epitope: N-Terminus   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Rat	Monoclonal	Mouse	WB	Caspase 4 Antibody [17D9] LS-C106831 Rat Monoclonal (1) 25 µg - 230.00 100 µg - 350.00 Applications: WB Epitope:   Reactivity: Mu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	ICC, IHC-P, WB	Caspase 4 Antibody LS-C185344 Rabbit Polyclonal (3) 100 µl - 335.00 Applications: IHC-P, ICC, WB Epitope: aa68-162   Reactivity: Hu Format:
Caspase 4	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, WB	Caspase 4 Antibody LS-C177726 Rabbit Polyclonal (2) 100 µl - 345.00 Applications: IHC, WB Epitope: Glu124   Reactivity: Hu, Mu, Rt Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	IHC, WB	Caspase 4 Antibody LS-C26866 Rabbit Polyclonal (1) 100 µg - 360.00 Applications: IHC, WB Epitope:   Reactivity: Hu Format: Unconjugated
Caspase 4	Rat	Monoclonal	Mouse, Rat	IHC-Fr, IP, WB	Caspase 4 Antibody LS-C77957 Rat Monoclonal 100 µl - 480.00 Applications: IHC-Fr, WB, IP Epitope:   Reactivity: Mu, Rt Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse	IHC-P, WB	Caspase 4 Antibody LS-C121481 Rabbit Polyclonal 100 µg - 660.00 Applications: IHC-P, WB Epitope: N-Terminus   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse	IHC-P, WB	Caspase 4 Antibody LS-C121482 Rabbit Polyclonal 100 µg - 435.00 Applications: IHC-P, WB Epitope: N-Terminus   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	ELISA, WB	Caspase 4 Antibody LS-C136842 Rabbit Polyclonal (1) 100 µl - 255.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	ELISA, WB	Caspase 4 Antibody LS-C136843 Rabbit Polyclonal (1) 100 µl - 255.00 Applications: WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	ELISA, WB	Caspase 4 Antibody LS-C121051 Rabbit Polyclonal (1) 100 µg - 295.00 Applications: WB, ELISA Epitope: Internal   Reactivity: Hu Format: Unconjugated
Caspase 4	Goat	Polyclonal	Human	ELISA, WB	Caspase 4 Antibody LS-C54611 Goat Polyclonal (1) 100 µg - 295.00 Applications: WB, ELISA Epitope: Internal   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Mouse, Rat	WB	Caspase 4 Antibody LS-C48133 Rabbit Polyclonal (1) 100 µg - 385.00 Applications: WB Epitope:   Reactivity: Mu, Rt Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse, Rat	WB	Caspase 4 Antibody LS-C48139 Rabbit Polyclonal (1) 100 µg - 385.00 Applications: WB Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
Caspase 4	Mouse	Monoclonal	Human	WB	Caspase 4 Antibody LS-C48312 Mouse Monoclonal (1) 100 µg - 455.00 Applications: WB Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
Caspase 4	Rat	Monoclonal	Mouse	Flo	Caspase 4 Antibody [17D9] LS-C105950 Rat Monoclonal (1) 25 µg - 240.00 100 µg - 380.00 Applications: Flo Epitope:   Reactivity: Mu Format: PE
Caspase 4	Rabbit	Polyclonal	Human	WB	Caspase 4 Antibody LS-C116924 Rabbit Polyclonal (1) 50 µg - 380.00 Applications: WB Epitope: Internal   Reactivity: Hu Format: Unconjugated
Caspase 4	Mouse	Monoclonal	Human	WB	Caspase 4 Antibody [4B9] LS-C179762 Mouse Monoclonal (1) 100 µg - 335.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse	WB	Caspase 4 Antibody LS-C168331 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: aa277-306   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human, Mouse	WB	Caspase 4 Antibody LS-C168332 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: aa37-66   Reactivity: Hu, Mu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	WB	Caspase 4 Antibody LS-C63131 Rabbit Polyclonal 25 µg - 115.00 100 µg - 255.00 Applications: WB Epitope: aa85-101   Reactivity: Hu Format: Unconjugated
Caspase 4	Rat	Monoclonal	Mouse, Rat	Flo, WB	Caspase 4 Antibody LS-C35306 Rat Monoclonal 100 µg - 485.00 Applications: WB, Flo Epitope:   Reactivity: Mu, Rt Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Mouse	ELISA, WB	Caspase 4 Antibody LS-C35307 Rabbit Polyclonal 100 µg - 550.00 Applications: WB, ELISA Epitope: C-Terminus   Reactivity: Mu Format: Unconjugated
Caspase 4	Mouse	Monoclonal	Human	ELISA, WB	Caspase 4 Antibody LS-C77878 Mouse Monoclonal 50 µl - 495.00 Applications: WB, ELISA Epitope: aa119-133   Reactivity: Hu Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Mouse, Rat	WB	Caspase 4 Antibody LS-C35304 Rabbit Polyclonal 100 µg - 480.00 Applications: WB Epitope: aa202-217   Reactivity: Mu, Rt Format: Unconjugated
Caspase 4	Rabbit	Polyclonal	Human	WB	Caspase 4 Antibody LS-C77873 Rabbit Polyclonal 100 µg - 590.00 Applications: WB Epitope: Internal   Reactivity: Hu Format: Unconjugated

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Caspase 4 Feature Table

Feature Type	Location	Details
Function	1 - 377	Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.
Modification	83 - 83	Phosphoserine
Molecular Weight	1 - 377	43262
Similarity	1 - 377	Belongs to the peptidase C14A family.
Similarity	1 - 377	Contains 1 CARD domain.
Subunit	1 - 377	Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a small and a large subunit (By similarity).
Tissue Specificity	1 - 377	Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.

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