Unfortunately, the antibody LS-C12502 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.

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CASP7 / Caspase 7 Antibodies

caspase 7, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.

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CASP7 / Caspase 7 Antibodies (33)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
CASP7 / Caspase 7	Mouse	Monoclonal	Human	IHC-P, WB	CASP7 / Caspase 7 Antibody [7-1-11] LS-B3670 Mouse Monoclonal (3) 50 µg - 385.00 Applications: IHC-P, WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, IHC-P, WB	CASP7 / Caspase 7 Antibody LS-B3794 Rabbit Polyclonal (3) 50 µg - 385.00 Applications: IHC, IHC-P, WB Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	IHC-P, WB	CASP7 / Caspase 7 Antibody LS-B3795 Rabbit Polyclonal (3) 50 µg - 385.00 Applications: IHC-P, WB Epitope: N-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human	IHC-P, WB	CASP7 / Caspase 7 Antibody [10-1-62] LS-B3671 Mouse Monoclonal (2) 50 µg - 385.00 Applications: IHC-P, WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human	IHC-P, WB	CASP7 / Caspase 7 Antibody [25B881.1] LS-B2020 Mouse Monoclonal (3) 50 µg - 385.00 Applications: IHC-P, WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rat	Monoclonal	Human	IHC-P, WB	CASP7 / Caspase 7 Antibody [20F3] LS-B4060 Rat Monoclonal (2) 50 µg - 385.00 Applications: IHC-P, WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human, Mouse, Rat	IHC-P, WB	CASP7 / Caspase 7 Antibody LS-B239 Mouse Monoclonal (1) 100 µl - 385.00 Applications: IHC-P, WB Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Monoclonal	Human	ICC, IHC-P, IP, WB	CASP7 / Caspase 7 Antibody [E22] LS-C49363 Rabbit Monoclonal (3) 100 µl - 415.00 Applications: IHC-P, ICC, WB... Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse	ELISA, IHC-P, WB	CASP7 / Caspase 7 Antibody LS-C121032 Rabbit Polyclonal (2) 100 µg - 295.00 Applications: IHC-P, WB, ELISA Epitope: Internal   Reactivity: Hu, Mu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse	ELISA, IHC-P, WB	CASP7 / Caspase 7 Antibody LS-C121033 Rabbit Polyclonal (2) 100 µg - 295.00 Applications: IHC-P, WB, ELISA Epitope: Internal   Reactivity: Hu, Mu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Monoclonal	Human	ICC, IHC-P, WB	CASP7 / Caspase 7 Antibody [Y33] LS-C105218 Rabbit Monoclonal (2) 100 µl - 415.00 Applications: IHC-P, ICC, WB Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Rat	IHC, WB	CASP7 / Caspase 7 Antibody LS-C177592 Rabbit Polyclonal (2) 100 µl - 345.00 Applications: IHC, WB Epitope: Met45   Reactivity: Hu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, IHC	CASP7 / Caspase 7 Antibody LS-C137030 Rabbit Polyclonal (1) 100 µl - 255.00 Applications: IHC, ELISA Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Gerbil, Human, Mouse, Rat	IHC-Fr, IHC-P, IP, WB	CASP7 / Caspase 7 Antibody LS-C148244 Rabbit Polyclonal (1) 50 µl - 295.00 Applications: IHC-Fr, IHC-P, WB... Epitope:   Reactivity: Gb, Hu, Mu ... Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	IHC, IP, WB	CASP7 / Caspase 7 Antibody LS-C48212 Rabbit Polyclonal (1) 100 µg - 485.00 Applications: IHC, WB, IP Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	IHC-P, WB	CASP7 / Caspase 7 Antibody LS-C43133 Rabbit Polyclonal 100 µg - 320.00 Applications: IHC-P, WB Epitope: C-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human	ELISA, IHC	CASP7 / Caspase 7 Antibody LS-C137151 Rabbit Polyclonal 100 µl - 255.00 Applications: IHC, ELISA Epitope: C-Terminus   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human, Mouse, Rat	IP, WB	CASP7 / Caspase 7 Antibody [4G2] LS-C179785 Mouse Monoclonal (2) 100 µg - 335.00 Applications: WB, IP Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human	WB	CASP7 / Caspase 7 Antibody LS-C98874 Rabbit Polyclonal (2) 100 µg - 290.00 Applications: WB Epitope: Internal   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse	ELISA, WB	CASP7 / Caspase 7 Antibody LS-C121054 Rabbit Polyclonal (1) 100 µg - 295.00 Applications: WB, ELISA Epitope: Internal   Reactivity: Hu, Mu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human	WB	CASP7 / Caspase 7 Antibody LS-C135480 Rabbit Polyclonal (1) 50 µg - 380.00 Applications: WB Epitope: N-Terminus   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse	WB	CASP7 / Caspase 7 Antibody LS-C98875 Rabbit Polyclonal (1) 100 µg - 290.00 Applications: WB Epitope: C-Terminus   Reactivity: Hu, Mu Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human	WB	CASP7 / Caspase 7 Antibody LS-C26687 Mouse Monoclonal (1) 100 µg - 330.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	WB	CASP7 / Caspase 7 Antibody LS-C48206 Rabbit Polyclonal (1) 100 µg - 385.00 Applications: WB Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human, Mouse, Rat	IP, WB	CASP7 / Caspase 7 Antibody LS-C48124 Mouse Monoclonal 100 µg - 455.00 Applications: WB, IP Epitope:   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human	IP, WB	CASP7 / Caspase 7 Antibody [7CSP01] LS-C95559 Mouse Monoclonal 0.5 ml - 330.00 1 ml - 445.00 Applications: WB, IP Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human	WB	CASP7 / Caspase 7 Antibody LS-C26459 Rabbit Polyclonal 100 µg - 330.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human	WB	CASP7 / Caspase 7 Antibody LS-C26654 Mouse Monoclonal 100 µg - 330.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, ICC, IP, WB	CASP7 / Caspase 7 Antibody LS-C12507 Rabbit Polyclonal 100 µl - 440.00 Applications: ICC, WB, IP... Epitope: N-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, Flo, WB	CASP7 / Caspase 7 Antibody LS-C12506 Rabbit Polyclonal 100 µl - 405.00 Applications: WB, Flo, ELISA Epitope: Cleavage Site   Reactivity: Hu, Mu, Rt Format: Unconjugated
CASP7 / Caspase 7	Mouse	Monoclonal	Human	WB	CASP7 / Caspase 7 Antibody LS-C77900 Mouse Monoclonal 100 µg - 510.00 Applications: WB Epitope:   Reactivity: Hu Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Rat	WB	CASP7 / Caspase 7 Antibody LS-C77901 Rabbit Polyclonal 100 µg - 590.00 Applications: WB Epitope: C-Terminus   Reactivity: Hu, Rt Format: Unconjugated
CASP7 / Caspase 7	Rabbit	Polyclonal	Human, Mouse, Rat	WB	CASP7 / Caspase 7 Antibody LS-C77902 Rabbit Polyclonal 100 µg - 590.00 Applications: WB Epitope: N-Terminus   Reactivity: Hu, Mu, Rt Format: Unconjugated

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CASP7 / Caspase 7 Feature Table

Feature Type	Location	Details
Function	1 - 303	Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Modification	2 - 2	N-acetylalanine
Modification	16 - 16	Phosphoserine
Molecular Weight	1 - 303	34277
Similarity	1 - 303	Belongs to the peptidase C14A family.
Subcellular Location	1 - 303	Cytoplasm.
Subunit	1 - 303	Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 11 kDa (p11) subunit.
Tissue Specificity	1 - 303	Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.

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