ABCC3 / MRP3 Antibodies

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

MRP3 is a member of the human multidrug resistance protein gene family. It is an organic anion and multidrug transporter predominantly localized to the basolateral membrane of polarized epithelial cells. MRP3 is up regulated in certain tumors, liver cells under cholestatic conditions, keratinocytes during wound healing, and in MRP2 deficient Dubin-Johnson patients.

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ABCC3 / MRP3 Antibodies (7)

Target	Host	Clonality	Format	Epitope	Reactivity	Applications
ABCC3 / MRP3	Rabbit	Polyclonal	Human	ELISA, IHC-P, WB	ABCC3 / MRP3 Antibody LS-B7540 Rabbit Polyclonal (1) 50 µg - 385.00 Applications: IHC-P, WB, ELISA Epitope:   Reactivity: Hu Format: Unconjugated
ABCC3 / MRP3	Rabbit	Polyclonal	Human	Flo, IHC, WB	ABCC3 / MRP3 Antibody LS-C155848 Rabbit Polyclonal (3) 100 µg - 290.00 Applications: IHC, WB, Flo Epitope: aa906-933   Reactivity: Hu Format: Unconjugated
ABCC3 / MRP3	Mouse	Monoclonal	Human	ELISA, Flo, ICC, IF, IHC-Fr, WB	ABCC3 / MRP3 Antibody LS-C16477 Mouse Monoclonal 250 µg - 710.00 Applications: IHC-Fr, ICC, IF... Epitope: aa830-949   Reactivity: Hu Format: Unconjugated
ABCC3 / MRP3	Mouse	Monoclonal	Human	Flo, ICC, IHC-Fr, WB	ABCC3 / MRP3 Antibody [M3II-21] LS-C124146 Mouse Monoclonal 1000 µl - 590.00 Applications: IHC-Fr, ICC, WB... Epitope: aa830-949   Reactivity: Hu Format: Unconjugated
ABCC3 / MRP3	Mouse	Monoclonal	Human	Flo, ICC, IHC-Fr, WB	ABCC3 / MRP3 Antibody [M3II-9] LS-C124147 Mouse Monoclonal 1000 µl - 590.00 Applications: IHC-Fr, ICC, WB... Epitope:   Reactivity: Hu Format: Unconjugated
ABCC3 / MRP3	Rabbit	Polyclonal	Human	WB	ABCC3 / MRP3 Antibody LS-C102044 Rabbit Polyclonal (1) 50 µg - 380.00 Applications: WB Epitope: Internal   Reactivity: Hu Format: Unconjugated
ABCC3 / MRP3	Rabbit	Polyclonal	Human	WB	ABCC3 / MRP3 Antibody LS-C177398 Rabbit Polyclonal (1) 100 µl - 345.00 Applications: WB Epitope: Leu1010   Reactivity: Hu Format: Unconjugated

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ABCC3 / MRP3 Feature Table

Feature Type	Location	Details
Function	1 - 1527	May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity).
Modification	908 - 908	Phosphoserine (By similarity)
Molecular Weight	1 - 1527	169343
Similarity	1 - 1527	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Similarity	1 - 1527	Contains 2 ABC transmembrane type-1 domains.
Similarity	1 - 1527	Contains 2 ABC transporter domains.
Subcellular Location	1 - 1527	Membrane; Multi-pass membrane protein.
Tissue Specificity	1 - 1527	Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney.

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