ABL1 Antibody (LS-C49588)
|
Technical Help 
Print Version 
PDF 
|
|
Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Rabbit anti-Human Monoclonal (Y421) Antibody - LS-C49588 - LSBio |
|
|
Antibody Details
|
| Antibody Catalog ID: |
LS-C49588 |
| Antibody Target: |
Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) |
| Synonyms: |
ABL1, Abl, Bcr-Abl, c-abl, jtk7, p150, proto-oncogene tyrosine-protein kinase abl, v-abl, v-abl abelson murine leukemia viral oncogene homolog 1 |
| Family: |
Protein Kinase |
| Subfamily: |
Abl |
| Host: |
ABL1 antibody was produced in Rabbit |
| Antigen Species: |
ABL1 antibody was raised against Human |
| Clonality: |
Monoclonal |
| Isotype: |
IgG |
| Antibody Clone Name: |
Y421 |
| Antigen Type: |
Synthetic peptide |
| Immunogen: |
ABL1 antibody was raised against a synthetic peptide corresponding to residues in the protein kinase domain of human C-Abl was used as an immunogen. This antibody is predicted to detect both isoforms based on sequence analysis |
| Predicted Species Reactivity: |
Rat
|
| Purification: |
Tissue Culture Supernatant |
| Presentation: |
50 mM Tris-glycine, pH 7.4, 0.15 M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA. |
| Recommended Storage: |
Long term: -20°C; Short term: -20°C |
| Antibody Uses: |
Western blot (WB) (1:2000 ), Immunoprecipitation (IP) (1:50 ) (Optimal dilution to be determined by the researcher) |
| Size: |
100 µl |
| Antibody Price (USD): |
$350 |
|
|
Western Blot Image:
|
|
| Western blot analysis on K562 cell lysate using anti- c-Abl RabMAb, dilution 1:2,000. |
| |
|
Related Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibodies (37)
|
| Target | Catalog | Type | Form | Epitope | Assay | Reactivity | Size | Price | Buy |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-B1166 | Rabbit IgG | | Tyr412 | IHC-P | Human, Mouse | 50 µg | $350 |  |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-B2776 | Mouse IgG1 | | | WB, IP, IF, IHC-P | Human, Mouse | 50 µg | $350 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C33822 | Mouse IgG1 | | | IHC, WB, IP, ELISA, IF | Mouse, Human | 50 µg | $295 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C33821 | Rabbit | | | IHC, WB, IP, ELISA | Human, Mouse | 50 µg | $295 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C88554 | Mouse IgG1 | | SH2 Domain | WB, IP, IF, IHC-P | Human, Mouse | 20 µg | $250 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C88555 | Mouse IgG1 | Biotin | | WB, IP, IF, IHC-P | Human, Mouse | 20 µg | $280 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97399 | Rabbit | | pTyr134 | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97400 | Rabbit | | pTyr245 | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97401 | Rabbit | | pTyr251 | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99160 | Rabbit | | C-Terminus | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99162 | Rabbit | | Internal | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97398 | Rabbit | | pSer588 | IHC, ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97402 | Rabbit | | pTyr272 | ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97403 | Rabbit | | pTyr276 | ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C51272 | Rabbit IgG | | pTyr412 | IHC | Human, Mouse | 40 µg | $245 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C20984 | Rabbit IgG | | C-Terminus | ICC, IHC, IP | Human | 100 µl | $445 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77356 | Rabbit IgG | | | WB, IP, IHC-P | Human, Mouse | 500 µl | $470 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77351 | Rabbit IgG | | | IHC-P | Human, Mouse | 7000 µl | $480 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C109117 | Mouse IgG1 | | | WB, ELISA | Human | 100 µl | $320 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C53734 | Rabbit | | pTyr245 | WB | Human, Mouse | 10 blot | $488 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C53735 | Rabbit | | pTyr412 | WB | Human, Mouse | 10 blot | $488 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C45601 | Mouse IgG1 | | | WB, IP, IF | Human, Mouse | 100 µg | $365 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99159 | Rabbit | | N-Terminus | WB, ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99161 | Rabbit | | N-Terminus | WB, ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C96814 | Rabbit | | pTyr204 | ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C96835 | Rabbit | | pTyr283 | ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C96836 | Rabbit | | pThr754 | ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12193 | Rabbit IgG | | N-Terminus | ICC, WB, Flo, ELISA | Human, Mouse, Rat | 100 µl | $405 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12199 | Rabbit IgG | | C-Terminus | WB, IP, ELISA, IF | Human, Mouse, Rat | 100 µl | $405 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12200 | Rabbit IgG | | pTyr245 | WB, ELISA | Human, Mouse | 100 µl | $440 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C20249 | Rabbit IgG | | | WB, IP | Mouse, Human | 250 µg | $485 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C20250 | Rabbit IgG | | aa929-1020 | WB, IP | Mouse, Human | 250 µg | $485 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C34784 | Rabbit IgG | | | WB, Func | | 200 µg | $485 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12201 | Rabbit | | pTyr245 | WB | Human | 100 µl | $500 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12202 | Rabbit IgG | | pThr735 | WB | Human | 100 µl | $430 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77349 | Mouse IgG2a | | | WB | Human, Mouse, Rat | 100 µl | $450 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77354 | Rabbit IgG | | pTyr412 | WB | Human | 100 µl | $480 | |
|
|
Antibody Summary:
c-Abl is a nonreceptor tyrosine kinase that is located in either the nucleus or the cytoplasm depending on the splice isoform (1a and 1b). c-Abl is implicated in cell differentiation, division, adhesion and stress response. C-Abl is composed of a catalytic domain, a SH2 and SH3 domain and an actin binding domain. Alteration of ABL by chromosomal rearrangement (BCR-ABL) or viral transduction (v-Abl) causes chronic myeloid leukemia (CML) and leads to malignancy. cAbl has been known to play a role in the insulin signaling pathway through its interaction with SORBS1. It has also been shown that that the tyrosine kinase activity of nuclear c-Abl is regulated in the cell cycle through a specific interaction with the retinoblastoma protein (RB1); and can be activated by ionizing radiation and other DNA damaging agents such as DNA-PK and ATM. Powered by Epitomics Technology.
|
| Requested From: |
United States |
|
|