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RELA Antibody - V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Mouse anti-Human Monoclonal (112A1021 ) Antibody - LS-C537 - LifeSpan BioSciences

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Antibody Catalog ID: LS-C537
Antibody Target: V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA)
Synonyms: RELA, nfkb3, nuclear factor kappa-b, subunit 3, transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog a
Host: Mouse
Antigen Species: Human
Clonality: Monoclonal
Isotype: IgG1
Antibody Clone Name: 112A1021 
Antigen Type: Synthetic peptide - KLH conjugated
Immunogen: Synthetic peptide
Antibody Specificity: A synthetic peptide corresponding to amino acids 526-539 of human NF-kB (p65) protein. It will cross-react with mouse NF-kB p65.
Predicted Species Reactivity: Mouse
Purification: Protein G Column
Weight: 100 µg
Presentation: PBS, 0.2% gelatin, 0.05% sodium azide.
Recommended Storage: Long term: -70°C; Short term: +4°C
Antibody Uses: Western blot (WB) (2 µg/ml ), Flow Cytometry (Flo) (5 µg/ml ) (Optimal dilution to be determined by the researcher)
Antibody Price (USD): $225.00

Western Blot Image:



Western blot analysis of NF-kB (p65) using antibody at 2 µg/ml in 30 µg of A) Ramos, B) Daudi, C) HeLa and D) mouse NIH 3T3 cell lysate.
 


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Antibody Summary:
NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The active nuclear form of the NF-kB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65.



For Research Use Only. Not intended for human, diagnostic or therapeutic purposes.
The data on this page have been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).
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