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ABL1 Antibody

Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Rabbit anti-Human Polyclonal (C-Terminus) Antibody - LS-C12199 - LifeSpan BioSciences

Antibody Technical Query IHC Request For Information Buy This Antibody
Antibody Catalog ID: LS-C12199
Antibody Target: Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1)
Synonyms: ABL1, Abl, Bcr-Abl, c-abl, jtk7, p150, proto-oncogene tyrosine-protein kinase abl, v-abl, v-abl abelson murine leukemia viral oncogene homolog 1
Family: Protein Kinase
Subfamily: Abl
Host: ABL1 antibody was produced in Rabbit
Antigen Species: ABL1 antibody was raised against Human
Clonality: Polyclonal
Isotype: IgG
Antigen Type: Synthetic peptide
Immunogen: ABL1 antibody was raised against synthetic peptide (KLH coupled) derived from the C-terminus of human c-Abl.
Antibody Specificity: Recognizes endogenous levels of Abl proteins. Species cross-reactivity: Human, mouse, rat and drosophila.
Antigen Modification: C-Terminus
Predicted Species Reactivity: Mouse, Rat
Purification: Protein A Column
Presentation: 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Recommended Storage: Long term: -20°C; Short term: +4°C
Antibody Usage Summary: Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunofluorescence. Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4?C with gentle shaking, overnight. Recognizes bands at 135kD (c-Abl) (210kD (Bcr-Abl)). Immunoprecipitation: 1:100. Immunofluorescence: 1:25.
Antibody Uses: Western blot (WB) (1:1000 ), Immunoprecipitation (IP) (1:100 ), Immunofluorescence (IF) (1:25 ), ELISA (Optimal dilution to be determined by the researcher)
Size: 100 µl
Antibody Price (USD): $405

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Antibody Summary:
Bcr-Abl hybrid gene product is a 210kD protein known to be assembled in the K562 (human chronic myelogenous leukemia) cell line. The c-Abl proto-oncogene encodes a nonreceptor type protein tyrosine kinase that is ubiquitously expressed and highly conserved in metazoan evolution. c-Abl protein is distributed in both the nucleus and the cytoplasm of cells. Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry . Other applications not tested. Detects overexpressed levels of Abl proteins. The antibody detects Abl proteins immunoprecipitated from various cell lines. It does not crossreact with other related tyrosine kinase family members. Species Crossreactivity: Human, mouse and rat.


Requested From: United States

For Research Use Only. Not intended for human, diagnostic or therapeutic purposes.
The data on this page have been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).
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