ABL1 Antibody
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Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Rabbit anti-Human Polyclonal (N-Terminus) Antibody - LS-C12193 - LifeSpan BioSciences
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| Antibody Catalog ID: |
LS-C12193 |
| Antibody Target: |
Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) |
| Synonyms: |
ABL1, Abl, Bcr-Abl, c-abl, jtk7, p150, proto-oncogene tyrosine-protein kinase abl, v-abl, v-abl abelson murine leukemia viral oncogene homolog 1 |
| Family: |
Protein Kinase |
| Subfamily: |
Abl |
| Host: |
ABL1 antibody was produced in Rabbit |
| Antigen Species: |
ABL1 antibody was raised against Human |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Antigen Type: |
Synthetic peptide |
| Immunogen: |
ABL1 antibody was raised against synthetic peptide (KLH coupled) corresponding to the N-terminal sequence of human Bcr. MW of Antigen: 130, 160kD |
| Antibody Specificity: |
Detects endogenous levels of total Bcr and the 210kD Bcr-Abl fusion protein. Species cross-reactivity: Human, mouse and rat.
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| Antigen Modification: |
N-Terminus
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| Predicted Species Reactivity: |
Mouse, Rat
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| Purification: |
Immunoaffinity Chromatography |
| Presentation: |
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, BSA, 50% glycerol. |
| Recommended Storage: |
Long term: -20°C; Short term: +4°C |
| Antibody Usage Summary: |
Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunocytochemistry. Western Blot: 1:1000. Immunocytochemistry: 1:100. Flow Cytometry: 1:25. |
| Antibody Uses: |
Immunocytochemistry (ICC) (1:100 ), Western blot (WB) (1:1000 ), Flow Cytometry (Flo) (1:25 ), ELISA (Optimal dilution to be determined by the researcher) |
| Size: |
100 µl |
| Antibody Price (USD): |
$405 |
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Related Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibodies (37)
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| Target | Catalog | Type | Form | Epitope | Assay | Reactivity | Size | Price | Buy |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-B1166 | Rabbit IgG | | Tyr412 | IHC-P | Human, Mouse | 50 µg | $350 |  |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-B2776 | Mouse IgG1 | | | WB, IP, IF, IHC-P | Human, Mouse | 50 µg | $350 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C33822 | Mouse IgG1 | | | IHC, WB, IP, ELISA, IF | Mouse, Human | 50 µg | $295 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C33821 | Rabbit | | | IHC, WB, IP, ELISA | Human, Mouse | 50 µg | $295 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C88554 | Mouse IgG1 | | SH2 Domain | WB, IP, IF, IHC-P | Human, Mouse | 20 µg | $250 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C88555 | Mouse IgG1 | Biotin | | WB, IP, IF, IHC-P | Human, Mouse | 20 µg | $280 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97399 | Rabbit | | pTyr134 | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97400 | Rabbit | | pTyr245 | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97401 | Rabbit | | pTyr251 | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99160 | Rabbit | | C-Terminus | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99162 | Rabbit | | Internal | WB, ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97398 | Rabbit | | pSer588 | IHC, ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97402 | Rabbit | | pTyr272 | ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C97403 | Rabbit | | pTyr276 | ELISA, IHC-P | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C51272 | Rabbit IgG | | pTyr412 | IHC | Human, Mouse | 40 µg | $245 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C20984 | Rabbit IgG | | C-Terminus | ICC, IHC, IP | Human | 100 µl | $445 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77356 | Rabbit IgG | | | WB, IP, IHC-P | Human, Mouse | 500 µl | $470 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77351 | Rabbit IgG | | | IHC-P | Human, Mouse | 7000 µl | $480 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C49588 | Rabbit IgG | | | WB, IP | Human, Rat | 100 µl | $350 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C109117 | Mouse IgG1 | | | WB, ELISA | Human | 100 µl | $320 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C53734 | Rabbit | | pTyr245 | WB | Human, Mouse | 10 blot | $488 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C53735 | Rabbit | | pTyr412 | WB | Human, Mouse | 10 blot | $488 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C45601 | Mouse IgG1 | | | WB, IP, IF | Human, Mouse | 100 µg | $365 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99159 | Rabbit | | N-Terminus | WB, ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C99161 | Rabbit | | N-Terminus | WB, ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C96814 | Rabbit | | pTyr204 | ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C96835 | Rabbit | | pTyr283 | ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C96836 | Rabbit | | pThr754 | ELISA | Human | 100 µg | $267 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12199 | Rabbit IgG | | C-Terminus | WB, IP, ELISA, IF | Human, Mouse, Rat | 100 µl | $405 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12200 | Rabbit IgG | | pTyr245 | WB, ELISA | Human, Mouse | 100 µl | $440 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C20249 | Rabbit IgG | | | WB, IP | Mouse, Human | 250 µg | $485 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C20250 | Rabbit IgG | | aa929-1020 | WB, IP | Mouse, Human | 250 µg | $485 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C34784 | Rabbit IgG | | | WB, Func | | 200 µg | $485 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12201 | Rabbit | | pTyr245 | WB | Human | 100 µl | $500 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C12202 | Rabbit IgG | | pThr735 | WB | Human | 100 µl | $430 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77349 | Mouse IgG2a | | | WB | Human, Mouse, Rat | 100 µl | $450 | |
| Abelson Murine Leukemia Viral Oncogene Homolog 1 (ABL1) Antibody | LS-C77354 | Rabbit IgG | | pTyr412 | WB | Human | 100 µl | $480 | |
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Antibody Summary:
The Bcr gene was orginally identified by its presence in the chimeric Bcr-Abl oncogene (1). The N-terminal part of Bcr contains an oligomerization domain, a serine/threonine kinase domain and a region that binds SH2 domain. The middle of the protein has a PH domain and a region of sequence similarity to the guanine nucleotide exchange factors for the Rho family of GTP binding proteins. The C-terminal part may be involved in a GTPase-activating function for the small GTP-binding protein Rac (2,3). The function of Wildtype Bcr in cells remains unclear. PDGF receptor may use Bcr as a downstrean signal mediator (4). The Bcr-Abl fusion results in production of a constitutively active tyrosine kinase, which causes chronic myelogenous leukemia (CML) (5). Tyrosine 177 of Bcr is phosphorylated in Bcr-Abl fusion protein, which plays an important role in transforming the activity of Bcr-Abl Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunocytochemistry. Other applications not tested. Detects endogenous levels of total Bcr and the 210kD Bcr-Abl fusion protein. Species Crossreactivity: Human, mouse and rat.
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| Requested From: |
United States |
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