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AQP7 Antibody

Aquaporin 7 (Aqp7) Rabbit anti-Human Polyclonal (N-Terminus) Antibody - LS-C11961 - LifeSpan BioSciences

Antibody Technical Query IHC Request For Information Buy This Antibody
Antibody Catalog ID: LS-C11961
Antibody Target: Aquaporin 7 (Aqp7)
Synonyms: AQP7, Aqp7, aquaporin 7
Family: Transporter
Subfamily: Aquaporin
Host: AQP7 antibody was produced in Rabbit
Antigen Species: AQP7 antibody was raised against Human
Clonality: Polyclonal
Isotype: IgG
Antigen Type: Synthetic peptide
Immunogen: AQP7 antibody was raised against synthetic peptide 20aa sequence within the N-terminal domain of human Aquaporin, adipose specific (KLH coupled). This domain is predicted to be cytoplasmic.
Antibody Specificity: Recognizes Aquaporin, adipose specific. The peptide sequence is unique to Aquaporin, adipose specific with no significant homology to any other Aquaporins. Species cross-reactivity: Human.
Antigen Modification: N-Terminus
Purification: Immunoaffinity Chromatography
Presentation: 100 mM Tris, pH 7.4, 0.2% BSA, 0.1% sodium azide, 40% glycerol.
Recommended Storage: Long term: -20°C; Short term: +4°C
Antibody Usage Summary: Suitable for use in ELISA, Western Blot. Western Blot:1-10 ug/ml (ECL). Note: Recommend the use of 0.5-1% milk in all primary/secondary antibody-enzyme conjugate incubations in order to suppress non-specific bands. ELISA: 1:50000-1:100000. Control peptide can be used to coat ELISA plates at 1-10 ug/ml.
Antibody Uses: Western blot (WB) (1 - 10 µg/ml ), ELISA (1:50000 - 1:100000 ) (Optimal dilution to be determined by the researcher)
Size: 50 µg
Antibody Price (USD): $440

Related Aquaporin 7 (Aqp7) Antibodies (7)
TargetCatalogTypeFormEpitopeAssayReactivitySizePriceBuy
Aquaporin 7 (Aqp7) AntibodyLS-C11962Chicken IgYN-TerminusIHC, WB, ELISAHuman50 µg$440
Aquaporin 7 (Aqp7) AntibodyLS-C20765Chicken IgYN-TerminusIHC, WB, ELISARat50 µg$440
Aquaporin 7 (Aqp7) AntibodyLS-C11963Rabbit IgGN-TerminusWB, ELISAHuman50 µl$415
Aquaporin 7 (Aqp7) AntibodyLS-C11964Chicken IgYN-TerminusWB, ELISAHuman50 µl$415
Aquaporin 7 (Aqp7) AntibodyLS-C20764Rabbit IgGN-TerminusWB, ELISARat50 µg$440
Aquaporin 7 (Aqp7) AntibodyLS-C20766Rabbit IgGN-TerminusWB, ELISARat50 µl$415
Aquaporin 7 (Aqp7) AntibodyLS-C20767Chicken IgYN-TerminusWB, ELISARat50 µl$415

Antibody Summary:
Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. AQP0 or MIP26 (major intrinsic protein 26kD), and Aquaporin-1 (AQP1, purified from red cells) also called CHIP-28 (channel forming integral protein, 28kD; 268aa; gene locus 7p14) has been the foundation of the growing family of aquaporin. The lens specific AQP0 represents up to 80% of total lens membrane protein. Defects in MIP26 are cause of autosomal dominant cataract. The cataract Fraser mutation (CAT-FR or Shriveled) is a transposon-induced splicing error that substitutes a long terminal repeat sequence for the c-terminus of MIP. The lens opacity mutation (LOP) is an amino acid substitution that inhibits targeting of MIP to the cell membrane. Most recently, adipose specific AQP-adipose (342aa; AQPAP or AQP7-like) has been cloned. It facilities water and glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N- and C-terminus are predicted to be cytoplasmic. Suitable for use in ELISA, Western Blot. Other applications not tested. Recognizes Aquaporin, adipose specific. The peptide sequence is unique to Aquaporin, adipose specific with no significant homology to any other Aquaporins. Species Crossreactivity: Human.


Requested From: United States

For Research Use Only. Not intended for human, diagnostic or therapeutic purposes.
The data on this page have been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).
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