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AGTR1 Antibody

Angiotensin II Type 1 Receptor (AGTR1) Chicken anti-Rat Polyclonal (N-Terminus) Antibody - LS-C11860 - LifeSpan BioSciences

Antibody Technical Query IHC Request For Information Buy This Antibody
Antibody Catalog ID: LS-C11860
Antibody Target: Angiotensin II Type 1 Receptor (AGTR1)
Synonyms: AGTR1, agtr1a, agtr1b, ang ii receptor type 1a, angiotensin ii type 1b receptor, angiotensin ii receptor type 1a, angiotensin ii receptor type 1b, angiotensin ii receptor, vascular type 1, Angiotensin II Type 1 Receptor, angiotensin ii type 1a receptor, angiotensin receptor 1, angiotensin receptor 1a, angiotensin receptor 1b, AT1 receptor, at1a, at1a receptor, at1b, at1b receptor, at1r, at2r1, at2r1a, at2r1b, type-1a angiotensin ii receptor, type-1b angiotensin ii receptor
Family: GPCR
Subfamily: Angiotensin
Host: AGTR1 antibody was produced in Chicken
Antigen Species: AGTR1 antibody was raised against Rat
Clonality: Polyclonal
Isotype: IgY
Antigen Type: Synthetic peptide
Immunogen: AGTR1 antibody was raised against a 10 amino acid peptide sequence mapping near the N-terminus of rat AT II (1). This peptide is predicted to be extracellular. The peptide was coupled with KLH (carrier protein)
Antibody Specificity: The 10 AA rat immunogenic peptide is 100% identical in mouse, rat, human, porcine and rabbit. The sequence is the same in all AT II receptor isoforms (Type 1a, 1b and 1c). It has no sequence homology with other G-protein coupled receptors. Actual cross-reactivity of antibodies in all species is not established.
Antigen Modification: N-Terminus
Predicted Species Reactivity: Human, Mouse, Porcine, Rabbit
Purification: Unpurified Serum
Presentation: Neat serum, 40% glycerol.
Recommended Storage: Long term: -20°C; Short term: +4°C
Antibody Usage Summary: Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 ug/ml for affinity pure using ECL. The antibodies detected approx. 45-kD band. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
Antibody Uses: Western blot (WB) (1:1000 - 1:5000 ), ELISA (1:10000 - 1:100000 ) (Optimal dilution to be determined by the researcher)
Size: 50 µl
Antibody Price (USD): $415

Related Angiotensin II Type 1 Receptor (AGTR1) Antibodies (11)
TargetCatalogTypeFormEpitopeAssayReactivitySizePriceBuy
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C20633Mouse IgG1,kaa297-356ELISARat, Human1000 µg$328
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C11853Rabbit IgGN-TerminusIHC, WB, ELISA, IFRat, Human, Mouse, Porcine, Rabbit50 µl$400
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C84007Sheep aa297-359WB, IP, ELISAMouse, Rat250 µg$345
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C11861Chicken IgYN-TerminusIHC, WB, ELISARat, Human, Mouse, Porcine, Rabbit50 µg$440
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C85674Sheep WB, ELISA250 µg$380
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C11854Rabbit IgGN-TerminusWB, ELISARat, Dog, Human, Mouse, Porcine, Rabbit, Sheep50 µg$440
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C54459Goat InternalWB, ELISAHuman, Mouse, Rat100 µg$295
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C108588Rabbit InternalIHC, WB, ELISAHuman, Mouse, Rat100 µg$330
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C101948Rabbit IgGWB, ELISAHuman, Dog, Mouse, Rat50 µg$380
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C96196Rabbit ELISAHuman100 µg$345
Angiotensin II Type 1 Receptor (AGTR1) AntibodyLS-C20629Sheep IgGWB, ELISAHuman250 µg$470

Antibody Summary:
Angiotensin II mediates its action by interacting with membrane receptor, Angiotensin II type 1 receptors. The signal is transmitted via G-proteins that activates a phosphatidylinositol-calcium second messenger system. ATII receptors are integral membrane proteins of approx.359-363aa and predicted to contain at least 7 transmembrane domains. The N and C-terminus are predicted to extracellular and cytoplasmic, respectively. Three isoforms of ATII receptors have been cloned. In rat type 1a (359 aa) is expressed in the liver kidney, aorta, lung, uterus, ovary, spleen, heart, adrenal and vascular smooth muscles (1). Rat Type 1b (also known as AT3; 359 aa) is found in liver, kidney, and aorta (2). Type 1c (177 aa) has been detected in brain, kidney, liver, spleen and lung (3). Suitable for use in ELISA, Western Blotting. Other applications not tested. The 10 AA rat immunogenic peptide is 100% identical in mouse, rat, human, porcine and rabbit. The sequence is the same in all AT II receptor isoforms (Type 1a, 1b and 1c). It has no sequence homology with other G-protein coupled receptors. Actual crossreactivity of antibodies in all species is not established


Requested From: United States

For Research Use Only. Not intended for human, diagnostic or therapeutic purposes.
The data on this page have been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).
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