Optimal dilution to be determined by the researcher.
Specificity and Use
Recognizes the merozoite surface protein 1 (MSP1) of Plasmodium vivax, a protozoan parasite that causes malaria in humans. Malaria caused by P. vivax is seldom lethal but is the most common outside sub-Saharan Africa. The parasite is transmitted by Anopheles mosquitoes. Merozoites are the result of asexual reproduction of the parasite in the hepatocytes. They are released from hepatocytes and infected erythrocytes to infect other erythrocytes. MSP1 is the most abundant protein on the surface of merozoites and is involved in parasite invasion of the erythrocyte. It has long been considered a promising candidate for a vaccine against malaria. Some studies have shown that naturally acquired antibodies to a cleavage product of MSP1 can be linked to a reduced risk of clinical malaria