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Anti-LRP2 / Megalin Antibody IHC-plus™ LS-B105

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

LRP2 / Megalin Antibody LS-B105 Images

[click image for a larger image and more details]
Immunohistochemistry
Anti-Megalin antibody IHC of human kidney cortex.

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Rabbit Polyclonal to Human LRP2 / Megalin
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human LRP2 / Megalin
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Protein G purified

Applications

IHC - Paraffin (2.5 µg/ml), ELISA (1:000 - 1:1000)

Specificity and Use

LRP2 / Megalin antibody was raised against synthetic peptide from human LRP2 / Megalin.
Immunohistochemistry: LS-B105 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B105 was determined to be 2.5 ug/ml.

Packaging

PBS, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About LRP2 / Megalin

P98164 NM_004525 NP_004516.2

LRP2 Antibody, DBS Antibody, Glycoprotein 330 Antibody, gp330 Antibody, Megalin Antibody, LRP-2 Antibody, Calcium sensor protein Antibody

Megalin or low density lipoprotein-related protein 2 (LRP2), is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithelial tissues such as the kidney. Megalin has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase.

Immunohistochemistry

Immunohistochemistry
Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 10/21/2014

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